Template-Type: ReDIF-Article 1.0 Author-Name: M. Freick Author-Workplace-Name: Veterinary Practice Zettlitz, Zettlitz, Germany Author-Workplace-Name: Faculty Agriculture/Environment/Chemistry, HTW Dresden - University of Applied Sciences, Dresden, Germany †These authors contributed equally to this study Author-Name: M. Zenker Author-Workplace-Name: Veterinary Practice Zettlitz, Zettlitz, Germany Author-Name: O. Passarge Author-Workplace-Name: Veterinary Practice Zettlitz, Zettlitz, Germany Author-Name: J. Weber Author-Workplace-Name: Veterinary Practice Zettlitz, Zettlitz, Germany Title: Reducing the incidence of acute puerperal metritis in primiparous cows by application of pegbovigrastim in a Holstein dairy herd Abstract: In dairy cows, immunosuppression occurs frequently during the periparturient period and is characterised by transient neutropenia and impaired polymorphonuclear neutrophil function. As a consequence, postpartum cows are more susceptible to production-related diseases such as mastitis, retained foetal membranes and metritis. Recently, it has been shown that a double injection with recombinant bovine granulocyte colony-stimulating factor covalently bound to polyethylene glycol (PEG rbG-CSF) increased polymorphonuclear neutrophil number and the exocytosis of myeloperoxidase by stimulating polymorphonuclear neutrophil, which also played a role in innate uterine immune defence. The aim of this randomised clinical study was to investigate the effects of two periparturient PEG rbG-CSF injections (IMR; ImrestorTM, Elanco Animal Health, Bad Homburg/Germany) on the incidence of acute puerperal metritis, number of antibiotic doses required for treatment of acute puerperal metritis as well as parameters of milking performance (i.e., milk yield, milk fat, milk protein, and somatic cell count on the first dairy herd improvement test day) in primiparous cows within a dairy herd with an elevated incidence of acute puerperal metritis. In total, 169 heavily pregnant heifers were randomly assigned to the treatment group (IMR: n = 82) who received 15 mg PEG rbG-CSF subcutaneously 10 ± 3 days before the anticipated calving date and within 24 hours after calving, or to the untreated control group (Co: n = 87). In total, data from 157 animals (IMR: n = 75, Co: n = 82) were analysed. Administration of PEG rbG-CSF reduced the incidence of acute puerperal metritis in primiparous cows significantly (IMR: 22.7%, Co: 43.9%, P = 0.003; relative reduction: 48.3%). Moreover, the number of antibiotic doses per calving required for treatment of acute puerperal metritis was significantly lower in the pegbovigastrim group (IMR: 0.32 ± 0.66, Co: 0.59 ± 0.75, P = 0.005). No significant differences regarding incidence of clinical mastitis, milk production or milk composition were observed. These results suggest that further research should be performed to identify herd- and animal-specific factors that can be predictors of the beneficial effects of pegbovigrastim in preventing uterine diseases. Keywords: cattle, postpartum, uterine diseases, prevention, bovine granulocyte colony-stimulating factor, G-CSF Journal: Veterinární medicína Pages: 151-160 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/2/2018-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/2/2018-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0001.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:2-2018-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: D.E. Karcher Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Author-Name: R.C. Costa Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Author-Name: T.C. Prada Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Author-Name: P.C. Moraes Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Author-Name: L.A. Ramon Author-Workplace-Name: Faculty of Veterinary Medicine, Franca University, Franca, Brazil Author-Name: B.W. Minto Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Author-Name: L.G.G.G. Dias Author-Workplace-Name: Faculty of Agricultural and Veterinary Sciences, State University "Julio de Mesquita Filho"/ UNESP, Jaboticabal, Brazil Title: A modified technique for treating swimmer puppy syndrome Abstract: Swimmer puppy syndrome is an unusual anomaly that affects dogs within the first few days or months of life. This syndrome is characterised by the inability of the animal to maintain a quadrupedal position primarily using the pelvic limbs. In some cases, the condition may also affect the thoracic limbs. Although the exact pathophysiology of this condition remains uncertain, plausible causes include alterations in the neuromuscular synapse, improper myelination or poor development of peripheral motor neurons, delayed muscle development or ventral horn neuropathy. Here, we describe our results using a modified technique for the treatment of swimmer puppy syndrome, based on immobilisation for a period of one to four weeks with the aid of microporous hypoallergenic tapes, plasters and elastic meshes. Our modified method showed clear evidence of improvements. Keywords: canine, bandage, functional immobilisation, hyperextension, malformation, musculoskeletal disorder, rehabilitation Journal: Veterinární medicína Pages: 161-167 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/140/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/140/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0002.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:140-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: M. Goleman Author-Workplace-Name: Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, Lublin, Poland Author-Name: M. Karpinski Author-Workplace-Name: Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, Lublin, Poland Author-Name: P. Czyzowski Author-Workplace-Name: Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, Lublin, Poland Author-Name: W. Tuszynska-Bogucka Author-Workplace-Name: Faculty of Administration and Social Sciences, University of Economics and Innovations, Lublin, Poland Author-Name: L. Drozd Author-Workplace-Name: Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, Lublin, Poland Title: Reproductive parameters in Yorkshire terrier dogs in Poland Abstract: The aim of this study was to determine the basic reproductive parameters, i.e., litter size, gestation length, neonatal mortality rate and the type of delivery in Yorkshire terrier dogs, one of the most popular breeds in Poland. We have verified a hypothesis put forward by breeders that larger females have fewer whelping difficulties and produce larger litters and that pregnancies of females having one or two pups last longer. The focus of investigation was reproductive data from 66 Yorkshire terrier females registered in the Lublin Branch of the Polish Kennel Club, an FCI (Federation Cynologique Internationale) member, which whelped 124 litters comprising in total 508 pups from 37 fathers. The data were collected between August 2009 and December 2014. The significance of differences was verified using Mann-Whitney U and Kruskal-Wallis H-tests. The relationships between the recorded dogs' reproduction traits were estimated by calculation of Spearman's correlation coefficients with the use of the statistical programmes Statistica and SPSS 20. The investigations have confirmed the hypothesis concerning the larger litter size produced by larger females and the lower incidence of postpartum dystocia; however, the hypothesis of the impact of body weight on the length of pregnancy was rejected. The differences between the body weights of stud females and males reached 125%. The Yorkshire terrier appears to be a good reproductive breed with normal reproductive functions and good reproductive parameters. Keywords: small dog breeds, reproduction, litter size, completion of pregnancy Journal: Veterinární medicína Pages: 168-174 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/71/2016-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/71/2016-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0003.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:71-2016-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: A. Foglia Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: S. Del Magno Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: M. Pietra Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: V. Cola Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: M. Joechler Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: M. Morini Author-Workplace-Name: Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Italy Author-Name: L. Pisoni Title: Surgical treatment of a thoracic oesophageal duplication cyst causing recurrent dysphagia in an adult dog Abstract: A 7-year-old intact male Rottweiler dog was evaluated for recurrent dysphagia and regurgitation. Physical examination was unremarkable and routine blood works were within normal limits. Computed tomography revealed a defined lesion in the caudal mediastinum arising from the oesophagus. The lesion was excised using intercostal thoracotomy and the histological diagnosis was oesophageal duplication cyst. The dog recovered uneventfully and at a 3-year follow-up no clinical signs were reported. Although extremely rare, oesophageal duplication cysts should be considered in the differential diagnosis in cases of chronic regurgitation and dysphagia associated with evidence of an oesophageal lesion. Keywords: oesophagus, thoracic surgery, foregut anomaly Journal: Veterinární medicína Pages: 175-180 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/113/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/113/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0004.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:113-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: I.H. Yoon Author-Workplace-Name: Veterinary Medical Teaching Hospital, Konkuk University, Seoul, Republic of Korea Author-Name: H.J. Han Author-Workplace-Name: Veterinary Medical Teaching Hospital, Konkuk University, Seoul, Republic of Korea Author-Name: J.H. Kim Title: Successful management of refractory cough with the leukotriene receptor antagonist zafirlukast in a dog with chronic bronchitis: a case report Abstract: A 7-year-old spayed female Pomeranian dog was evaluated for a 6-month history of intractable coughing and dyspnoea. The cough was unresponsive to antibiotics and a bronchodilator medication prescribed by the previous animal hospital. No abnormalities were identified on the blood work, echocardiography and radiography. However, computed tomography revealed mild bronchiectasia. Based on the history, physical examination and non-specific diagnostic imaging findings, the dog was diagnosed with chronic bronchitis. The cough failed to resolve, despite an attempt to manage it with prednisolone, theophylline, codeine and N-acetylcysteine. With the owner's consent, we stopped all previous medications and finally tried the leukotriene receptor antagonist zafirlukast. The cough progressively improved and had mostly resolved four weeks after starting the administration of zafirlukast. The dog remained in complete remission without recurrence for seven months. This case report is the first to describe the successful long-term management of chronic cough with zafirlukast in a dog. Keywords: anti-inflammatory medicine, bronchiectasia, canine, glucocorticoid-intolerant, non-asthmatic bronchitis Journal: Veterinární medicína Pages: 181-186 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/162/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/162/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0005.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:162-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: S. Kim Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: E. Son Author-Workplace-Name: Jeil animal hospital, Seoul, Republic of Korea Author-Name: S. Lee Author-Workplace-Name: Jeil animal hospital, Seoul, Republic of Korea Author-Name: S. Lee Author-Workplace-Name: Jeil animal hospital, Seoul, Republic of Korea Author-Name: H. Kim Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: M. Kang Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: C. Lee Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: H. Park Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Title: Multiple myeloma associated with IgA lambda gammopathy and multiple myeloma oncogene 1 in a Yorkshire terrier Abstract: An eight-year-old spayed female Yorkshire terrier was presented with a one-month history of conspicuous weight-bearing lameness in the right hindlimb, mild anorexia, intermittent vomiting and marked polydipsia and polyuria. Radiographs revealed circular radiolucent foci of variable size in the skeleton. Haematological and serum biochemistry examination revealed mild leucopoenia with severe neutropaenia, mild non-regenerative anaemia, moderate thrombocytopoenia, moderate hyperglobulinaemia, mild hypoalbuminaemia, mild azotaemia and moderate hypercalcaemia. Quantification of serum immunoglobulins revealed elevated IgA and IgG. Serum protein electrophoresis showed a broad appearance with a β-region spike. Plasma cells accounted for 7.6% of the cells in the bone marrow. Serum immunofixation electrophoresis (IFE) revealed IgA lambda gammopathy. Immunohistochemistry in the bone marrow was diffusely positive for multiple myeloma oncogene 1 (MUM-1) and CD20. To our knowledge, this is first case report of multiple myeloma associated with IgA lambda gammopathy confirmed via IFE and immunohistochemical expression of MUM-1 in a dog. Keywords: dog, skeletal disease, pain, immunofixation electrophoresis, immunohistochemistry Journal: Veterinární medicína Pages: 187-192 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/152/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/152/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0006.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:152-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: T. Yaman Author-Name: A. Uyar Author-Workplace-Name: Faculty of Veterinary Medicine, University of Van Yuzuncu Yil, Van, Turkey Author-Name: O.F. Keles Author-Workplace-Name: Faculty of Veterinary Medicine, University of Van Yuzuncu Yil, Van, Turkey Author-Name: Z. Yener Author-Workplace-Name: Faculty of Veterinary Medicine, University of Van Yuzuncu Yil, Van, Turkey Title: Epithelioid and spindle-cell haemangioendothelioma in the brain of a dog: a case report Abstract: A 9.5-year-old male Belgian malinois dog died after showing clinical symptoms that included fatigue, anorexia and dyspnoea. Necropsy revealed macroscopic findings in the brain and other organs. A solitary, brown-red-coloured mass, approximately 0.5 cm thick and 1.5 × 2 cm in diameter, was detected on the right side of the medulla oblongata, pons and cerebellum. The cut surface showed no invasion of the brain parenchyma. Histologically, the neoplasm was characterised by proliferation of endothelial cells, which showed epithelioid and spindle cell features. Some tumour cells had intracytoplasmic lumen formations containing red blood cells. The nuclei of the tumour cells were large and vesicular. In immunohistochemical experiments the tumour cells stained positive for factor VIII-related antigen, CD31 and CD34. A description is provided of the features of this epithelioid and spindle-cell haemangioendothelioma (EHE) that originated from vessels of the meninges in the subarachnoid space. Keywords: haemangioendothelioma, spindle cell, CD34, canine, meninges Journal: Veterinární medicína Pages: 193-197 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/128/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/128/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0007.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:128-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: C.F. Agudelo Author-Workplace-Name: Faculty of Veterinary Medicine, Small Animal Clinic, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: Z. Filipejova Author-Workplace-Name: Faculty of Veterinary Medicine, Small Animal Clinic, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: L. Frgelecova Author-Workplace-Name: Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: O. Sychra Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Title: An unusual foreign body in a cat: a case report Abstract: Foreign bodies that affect airways are a well-recognised problem in small-animal practice. Cats in par­ticular, may be especially at risk of aspiration due to their predatory behaviour. Here, we report a case of an insect as a foreign body, namely a beetle in the tracheal bifurcation of a cat. Radiographs suggested a wide range of possibilities for differential diagnosis, but the presence of a foreign body was initially suspected. A final diagnosis was not pursued by the owner and the cat was euthanised. The presence of a summer chafer was then confirmed. To the authors' knowledge, this is the first time such a foreign body and radiographic findings are reported in the literature. Keywords: aspiration, beetle, dyspnoea, summer chafer Journal: Veterinární medicína Pages: 198-202 Volume: 63 Issue: 4 Year: 2018 DOI: 10.17221/8/2018-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/8/2018-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201804-0008.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:4:id:8-2018-VETMED