Template-Type: ReDIF-Article 1.0 Author-Name: S. Kovarikova Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Title: Indirect markers of glomerular filtration rate in dogs and cats: a review Abstract: Early diagnosis of kidney disease continues to be a subject of intense interest. Direct measurement of glomerular filtration rate is too complicated for first-line practices; thus, indirect markers of renal function have also been evaluated. Creatinine, traditionally measured as a readout of renal function, has limitations in its sensitivity. In dogs and cats, cystatin C became popular approximately 15 years ago, but recent reports question its usefulness, especially in cats. Symmetric dimethylarginine seems to be very promising as a marker of glomerular filtration rate with the ability to detect renal impairment earlier than creatinine. This article presents current knowledge of qualities, limitations, advantages and availability of novel and traditionally used biomarkers of glomerular filtration rate in dogs and cats. Keywords: creatinine, SDMA, cystatin C, kidney disease, feline, canine, dog, cat Journal: Veterinární medicína Pages: 395-412 Volume: 63 Issue: 9 Year: 2018 DOI: 10.17221/77/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/77/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201809-0001.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:9:id:77-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: M. Mrazova Author-Name: P. Rauser Author-Workplace-Name: Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: J. Burova Author-Workplace-Name: Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: M. Georgiou Author-Workplace-Name: Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: T. Fichtel Author-Workplace-Name: Small Animal Clinic, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Title: Influence of medetomidine, acepromazine, fentanyl and butorphanol on intraocular pressure and pupil size in healthy dogs Abstract: The aim of this study was to assess the effects of four different drugs used for anaesthesia premedication on intraocular pressure and pupil size in dogs. A prospective, randomised, double-blind clinical study was carried out. The subjects were forty client-owned healthy dogs (20 males and 20 females), aged 8.0 ± 2.9 years, with body weights of 11.8 ± 8.5 kg (mean ± SD) and without ocular abnormalities that were scheduled for periodontal treatment. Animals were randomly allocated into four groups and received intravenously either medetomidine 0.01 mg/kg, acepromazine 0.02 mg/kg, fentanyl 0.01 mg/kg or butorphanol 0.2 mg/kg. Intraocular pressure, pupil size, heart rate, respiratory frequency and systolic and diastolic arterial pressures were measured prior to (baseline) and at five and 10 minutes after premedication (T5, T10). Data were analysed by Anderson-Darling, Bartlett's, ANOVA and Dunnett's tests (P < 0.05). Significant increases of intraocular pressure were observed at T5 and T10 in the fentanyl group. Significant decreases of pupil size at T5 and T10 were detected in the fentanyl, butorphanol and medetomidine groups. In the fentanyl group, heart rate dropped significantly at T10, while respiratory frequency was elevated at T5 and T10. In the medetomidine group, heart rate and respiratory frequency were decreased at T5 and T10. In the butorphanol group, systolic arterial pressure was decreased at T5 and diastolic arterial pressure was decreased at T5 and T10. In the acepromazine group, systolic arterial pressure was decreased at T10. Within ten minutes after intravenous administration in healthy dogs, fentanyl significantly increased intraocular pressure and fentanyl, butorphanol and medetomidine decreased pupil size. Keywords: applanation tonometry, canine, sedation, opioids, ophthalmology Journal: Veterinární medicína Pages: 413-419 Volume: 63 Issue: 9 Year: 2018 DOI: 10.17221/51/2018-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/51/2018-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201809-0002.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:9:id:51-2018-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: M. Jerabek Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: P. Suchy Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: E. Strakova Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: L. Kudelkova Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: V. Simek Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: P. Jakesova Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: M. Machacek Author-Workplace-Name: Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic Author-Name: D. Zapletal Title: Selected blood biochemical indicators of Cherry Valley ducks undergoing fattening in relation to their diet and sex Abstract: The aim of the present study was to assess dietary and sex-related effects on selected blood indicators of 40-day-old mallard ducks undergoing fattening. The ducks were divided into three dietary groups (control, L50 and L100). The control (C) group was fed a diet containing soybean meal as the main protein component of the feed. In both experimental groups L50 and L100 soybean meal was replaced with meal of whole seeds of white lupine, Zulika variety, in proportions of 50 and 100%, respectively. With respect to the assessed dietary effect, the serum of the L50 group showed a significantly higher albumin concentration as compared to the C group (P < 0.05) accompanied by a significantly lower proportion of γ-globulins in the L50 group as compared to the L100 group (P < 0.01). As for the blood plasma, the C group showed a significantly higher concentration of total cholesterol as compared to the L100 group (P < 0.05) and a highly significant increase in the triacylglyceride (TAG) level as compared to the L50 and L100 groups (P < 0.01). Concerning plasma mineral indicators, ducks of the C group showed a significantly higher calcium concentration (P < 0.05) in comparison to the L100 group and a lower phosphorus concentration (P < 0.01) in comparison to the L50 as well as L100 group. Further, the C group showed a significantly lower level of potassium (K) as compared to the L50 group (P < 0.05) as well as the L100 group (P < 0.01). The sex of the ducks significantly (P < 0.05) affected the proportion of α-globulins in serum and the magnesium level in the plasma and affected the plasma levels of TAG and K and the activity of aspartate aminotransferase (P < 0.01). Keywords: hybrid mallard duck, dietary white lupine seeds, blood plasma indicators, serum protein fractions Journal: Veterinární medicína Pages: 420-432 Volume: 63 Issue: 9 Year: 2018 DOI: 10.17221/81/2018-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/81/2018-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201809-0003.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:9:id:81-2018-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: R. Meoli Author-Workplace-Name: Experimental Zooprophylactic Institute of Lazio and Tuscany "M. Aleandri", Rome, Italy Author-Name: C. Eleni Author-Workplace-Name: Experimental Zooprophylactic Institute of Lazio and Tuscany "M. Aleandri", Rome, Italy Author-Name: P. Cavicchio Author-Workplace-Name: Zoological Society of Pistoia, Pistoia, Italy Author-Name: M.C. Tonnicchia Author-Workplace-Name: Zoological Society of Pistoia, Pistoia, Italy Author-Name: B. Biancani Author-Workplace-Name: Park Oltremare, Riccione, Italy Author-Name: L. Galosi Author-Workplace-Name: School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy Author-Name: G. Rossi Author-Workplace-Name: School of Biosciences and Veterinary Medicine, University of Camerino, Matelica, Italy Title: B-cell chronic lymphocytic leukaemia in an African lion (Panthera leo) Abstract: A 15-year-old female African lion (Panthera leo) maintained at the Zoological Garden of Pistoia, Tuscany (Italy), showed signs of malaise, dyspnoea, tremors, pale mucous membranes and ataxia for two days prior to death. Complete blood count showed anaemia, thrombocytopaenia and severe lymphocytosis. At autopsy, the most relevant finding was severe, generalised splenomegaly. Histologically, high numbers of neoplastic lymphocytes diffusely infiltrated the spleen, liver, heart, pancreas, kidney and lungs. The lymphoid cells were positive for CD79a and negative for CD3 on immunohistochemistry. The histologic features of the neoplastic cells and their immunophenotype are consistent with B-cell lymphocytes. Based on surface membrane co-expression of immunoglobulin M and immunoglobulin D in most neoplastic cells, which indicated that they were naïve, antigen-inexperienced and mature circulating resting B-cells, and consistent with their appearance as small lymphocytes with high nuclear-to-cytoplasmic ratios, a diagnosis of B-cell chronic lymphocytic leukaemia was made. Keywords: lymphocytosis, feline, neoplastic disease Journal: Veterinární medicína Pages: 433-437 Volume: 63 Issue: 9 Year: 2018 DOI: 10.17221/144/2017-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/144/2017-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201809-0004.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:9:id:144-2017-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: S. Cagatay Author-Name: A.P. Gokce Author-Workplace-Name: Faculty of Veterinary Medicine, Near East University, Nicosia, Republic of Cyprus Author-Name: G. Yesilovali Author-Workplace-Name: Faculty of Veterinary Medicine, Near East University, Nicosia, Republic of Cyprus Title: Removal of a tracheal foreign body by intercostal thoracotomy in a cat Abstract: In this case report, we describe a five-year-old, mixed-breed, neutered male cat weighing 5.7 kg, that was referred to the Near East University Animal Hospital with complaints of dyspnoea, cough and lack of appetite over the preceding two days. Clinical examination revealed marked wheezing during expiration, severe shortness of breath and associated cyanosis. A blood sample was drawn for full blood count, serum biochemical and blood gas analyses. Laterolateral and ventrodorsal radiographic images of the thorax and abdominal region were obtained. A radiopaque foreign body measuring 3 × 9 × 13 mm was detected at the carina of the trachea, aligned in the midst of the fifth-sixth intercostal space. Considering that this foreign body obstructed the tracheal lumen almost completely and had been creating pressure on the tracheal wall for at least two days and also with the aim of preventing potential complications (tracheal rupture, laceration, etc.), after repeated unsuccessful interventions to minimise the time spent under anaesthesia, the object was removed by intercostal thoracotomy. The subject was discharged on the sixth postoperative day and regained its normal state within a short time. Keywords: aspiration, carina trachea, lower respiratory tract, pebble Journal: Veterinární medicína Pages: 438-442 Volume: 63 Issue: 9 Year: 2018 DOI: 10.17221/75/2018-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/75/2018-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-201809-0005.txt Handle: RePEc:caa:jnlvet:v:63:y:2018:i:9:id:75-2018-VETMED