Template-Type: ReDIF-Article 1.0 Author-Name: F Dadras Author-Workplace-Name: Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Research Institute of Fish Culture and Hydrobiology, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic Author-Name: J Velisek Author-Workplace-Name: Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Research Institute of Fish Culture and Hydrobiology, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic Author-Name: E Zuskova Author-Workplace-Name: Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Research Institute of Fish Culture and Hydrobiology, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czech Republic Title: An update about beneficial effects of medicinal plants in aquaculture: A review Abstract: Aquaculture is an essential and growing component of agricultural and global ecosystems worldwide. Aquaculture provides more than 25% of the total aquatic food consumption by humans. The development of the aquaculture industry should be followed in successive industrial years, and therefore it is necessary to pay attention to the management and type of farming system that is compatible with the environment. The use of antibiotics for disease control has been criticised for their negative effects, including the emergence of antibiotic-resistant bacteria, the suppression of the immune system and the environment, and the accumulation of residue in aquatic tissues. The use of these products reduces the need for treatments, enhances the effect of vaccines, and, in turn, improves production indicators. Medicinal plants have increasingly been used in recent years as a disease control strategy in aquaculture, boosting the immune system of aquatic animals and helping to develop strong resistance to a wide range of pathogens. Therefore, this review aims to provide an overview of the recent evidence on the beneficial use of medicinal plants to promote growth and strengthen the immune system in farmed aquatic animals. Keywords: disease, fish, growth, immunity, medicinal herb Journal: Veterinární medicína Pages: 449-463 Volume: 68 Issue: 12 Year: 2023 DOI: 10.17221/96/2023-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/96/2023-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202312-0001.txt Handle: RePEc:caa:jnlvet:v:68:y:2023:i:12:id:96-2023-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: W Zhang Author-Workplace-Name: Department of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China Author-Name: H Deng Author-Workplace-Name: Department of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China Author-Name: Y Liu Author-Workplace-Name: Department of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China Author-Name: S Chen Author-Workplace-Name: Department of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, P.R. China Author-Name: Y Liu Author-Workplace-Name: Department of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, P.R. China Author-Name: Y Zhao Author-Workplace-Name: Department of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, P.R. China Title: Ribavirin inhibits peste des petits ruminants virus proliferation in vitro Abstract: Peste des petits ruminants virus (PPRV), a member of the family Paramyxoviridae, belongs to the genus Morbillivirus. It causes devastating viral diseases in small ruminants and has been rapidly spreading over various regions in Africa, the Middle East, and Asia. Although vaccination is thought to be an effective management strategy against PPR infections, the heat sensitivity of PPRV vaccines severely restricts their use in regions with hot climates. In this research, we studied the antiviral activities of ribavirin and aimed to understand the potential mechanisms of action of ribavirin in the African green monkey kidney cells (Vero cells). In brief, the adsorption, intrusion, replication, and release of PPRV, as well as the mRNA expression level of RNA-dependent RNA polymerase (RdRp), were significantly inhibited in the ribavirin-treated Vero cells compared to those in the PPRV-infected cells that were not treated with ribavirin. Additionally, ribavirin has potential as an antiviral drug against PPRV, and its antiviral activity is mediated by the Janus kinase signal transducer and activator of transcription (JAK/STAT) and PI3K/AKT pathways. Keywords: antiviral activity, antiviral drugs, mechanism, peste des petits ruminants, signal pathway Journal: Veterinární medicína Pages: 464-476 Volume: 68 Issue: 12 Year: 2023 DOI: 10.17221/56/2023-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/56/2023-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202312-0002.txt Handle: RePEc:caa:jnlvet:v:68:y:2023:i:12:id:56-2023-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: T Novotna Author-Workplace-Name: Department of Animal Protection and Welfare and Veterinary Public Health, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Brno, Czech Republic Author-Workplace-Name: DRAVET, Veterinary Clinic, Drásov, Czech Republic Author-Name: B Sitarova Author-Workplace-Name: DRAVET, Veterinary Clinic, Drásov, Czech Republic Author-Name: Z Hoskova Author-Workplace-Name: Veterinary Clinic with Emergency Service MVDr. Lubomír Hošek, Brno, Czech Republic Author-Name: V Vaibarova Author-Workplace-Name: Department of Infectious Diseases and Microbiology, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czech Republic Author-Name: Z Dzuman Author-Workplace-Name: Department of Food Analysis and Nutrition, University of Chemistry and Technology, Prague, Czech Republic Author-Name: J Hajslova Author-Workplace-Name: Department of Food Analysis and Nutrition, University of Chemistry and Technology, Prague, Czech Republic Author-Name: V Skupien Author-Workplace-Name: Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czech Republic Author-Name: Z Svobodova Author-Workplace-Name: Department of Animal Protection and Welfare and Veterinary Public Health, Faculty of Veterinary Hygiene and Ecology, University of Veterinary Sciences Brno, Brno, Czech Republic Title: Tremorgenic mycotoxin poisoning in a dog: A case report Abstract: An eleven-year-old Pit Bull Terrier was presented to the veterinary practice with an acute onset of whole-body seizures. The clinical signs developed in a garden where the dog was kept that morning. There was a suspicion of tremorgenic mycotoxin poisoning by compost as the dog had vomited parts of compost right before the onset of the seizures and there was a pile of compost located in the garden. The dog underwent immediate decontamination following supportive treatment and recovered fully within 24 h of intensive care. The samples of the vomit and parts of the compost were cultivated. In the sample of the vomit, Penicillium sp. was found. Subsequently, tremorgenic mycotoxins paxilline, penitrem A and roquefortine C were determined chromatographically at significant concentrations in the vomit and a growth medium with cultivated Penicillium sp. The aim of this work is to describe the complex therapeutic and diagnostic approach to the patient with a suspected tremorgenic mycotoxin poisoning where a combination of mycological and chromatographic analyses was used to confirm the diagnosis. To the best of our knowledge, this is the first confirmed case of canine tremorgenic mycotoxicosis in the Czech Republic and the first reported case of paxilline poisoning in a dog. Keywords: chromatography, paxilline, Penicillium sp., penitrem A, roquefortine C Journal: Veterinární medicína Pages: 483-489 Volume: 68 Issue: 12 Year: 2023 DOI: 10.17221/82/2023-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/82/2023-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202312-0003.txt Handle: RePEc:caa:jnlvet:v:68:y:2023:i:12:id:82-2023-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: KR Kim Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: DH Kim Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: MJ Jung Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: DM Sihn Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: SW Jeong Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Author-Name: JH Kim Author-Workplace-Name: KU Animal Cancer Center, Konkuk University Veterinary Medical Teaching Hospital, Seoul, Republic of Korea Author-Workplace-Name: Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea Title: Canine oral melanoma with suspected pulmonary metastasis: Combination of immunotherapy and tyrosine kinase inhibitor treatment Abstract: This case report follows a 10-year-old castrated male Miniature Schnauzer dog presented with a history of incomplete surgical resection of an oral malignant melanoma (amelanotic type) on the right mandible. Melanoma vaccine therapy was administered due to incomplete surgical resection, however, new masses were detected on the contralateral mandible and suspected pulmonary metastasis occurred at 2 weeks and 7 months, respectively, following the first melanoma vaccination. At the time of detecting the pulmonary metastasis, targeted chemotherapy was initiated with the owner's consent using imatinib (10 mg/kg/day, p.o.), a tyrosine kinase inhibitor (TKI). The patient did not show any significant adverse events related to both anticancer treatments. Three months following the first dose of imatinib, the absence of the suspected pulmonary metastatic nodules on radiography indicated complete remission. In conclusion, this report describes the achievement of clinical remission of suspected pulmonary metastatic oral malignant melanoma and an extension of survival time in a dog given a combination treatment of immunotherapy and tyrosine kinase inhibitor. Keywords: dog, imatinib, malignant melanoma Journal: Veterinární medicína Pages: 477-482 Volume: 68 Issue: 12 Year: 2023 DOI: 10.17221/90/2023-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/90/2023-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202312-0004.txt Handle: RePEc:caa:jnlvet:v:68:y:2023:i:12:id:90-2023-VETMED