Template-Type: ReDIF-Article 1.0 Author-Name: P Zubricky Author-Workplace-Name: Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovak Republic Author-Name: A Balicka Author-Workplace-Name: Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovak Republic Author-Name: Z Drahovska Author-Workplace-Name: Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovak Republic Author-Name: M Lapsanska Author-Workplace-Name: Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovak Republic Author-Name: A Trbolova Author-Workplace-Name: Small Animal Clinic, University of Veterinary Medicine and Pharmacy in Kosice, Slovak Republic Title: Uveodermatological syndrome in dogs: A review of diagnosis, management, and ophthalmic patient needs Abstract: Uveodermatological syndrome is a widely recognised disease that continues to raise significant concern among both veterinarians and pet owners. Its aetiology, although still unclear, is believed to involve an autoimmune origin and genetic predisposition. The most common clinical signs include skin depigmentation, alopecia, poliosis, and, most frequently, granulomatous panuveitis. Affected dogs often develop secondary complications owing to persistent intraocular inflammation, such as cataracts and glaucoma. Although immunosuppressive therapy often yields a favourable response, recurrence is commonly observed. In some cases, uveodermatological syndrome presents a clinical challenge, as patients may experience adverse effects from medications, without which irreversible blindness may ensue. Keywords: autoimmune diseases, canine, depigmentation, uveitis Journal: Veterinární medicína Pages: 185-195 Volume: 70 Issue: 6 Year: 2025 DOI: 10.17221/10/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/10/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202506-0001.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:6:id:10-2025-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: AA Zaki Author-Workplace-Name: Department of Biomedical Sciences, College of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia Author-Workplace-Name: Department of Physiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt Author-Name: NM Alharbi Author-Workplace-Name: National Center for the Prevention & Control of Plants Pests & Animal Diseases, Buraydah, Qassim Region, Saudi Arabia Author-Name: TI Almundarij Author-Workplace-Name: Department of Biomedical Sciences, College of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia Author-Name: SM Albarrak Author-Workplace-Name: Department of Pathology and Laboratory Diagnosis, Collage of Veterinary Medicine, Qassim University, Buraydah, Saudi Arabia Title: Antioxidant and cytokine modulation in PCOS rats protected with probiotics, myo-inositol, and herbal extracts Abstract: This study investigated the pathophysiology of polycystic ovarian syndrome (PCOS) and evaluated the protective effects of various treatments in immature female Wistar rats (N = 48). The rats were divided into 6 groups: Olive oil injection (negative control, G1); testosterone propionate (TP)-induced PCOS (G2); probiotic + TP (G3); myo-inositol (myo-ins) + TP (G4); U. dioica extract + TP (G5); W. somnifera extract + TP (G6). The body weight, body weight gain, and percentage gain were measured weekly and then transformed using the base-10 logarithm (log10). TNF-α, IL-4, IL-10, and IL-17 were weekly measured using ELISA kits. Glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT) were analysed in the serum and liver extracts. The W. somnifera significantly reduced the TNF-α levels (P < 0.01). The probiotic and myo-ins significantly elevated the IL-10 levels (P < 0.01). Both plant extracts moderately restored the IL-10 levels. The probiotic and U. dioica administration significantly reduced the IL-17 levels (P < 0.01). The W. somnifera administration also decreased the IL-17 levels, though the effect was less pronounced than that of U. dioica. The probiotic, myo-ins, and W. somnifera groups exhibited enhanced CAT activity (P < 0.05). W. somnifera showed significant increases in the SOD and GSH-Px activities (P < 0.01), showing the most dramatic improvement. The use of these four treatments as a monotherapy in this study resulted in different changes. Therefore, further investigation is necessary to evaluate the protective effects of combining duos or trios of these treatments against this disease. Keywords: antioxidants, ELISA, immunity, myo-inositol, polycystic ovarian syndrome Journal: Veterinární medicína Pages: 203-217 Volume: 70 Issue: 6 Year: 2025 DOI: 10.17221/116/2024-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/116/2024-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202506-0002.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:6:id:116-2024-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: R Krejci Author-Workplace-Name: Ceva Sante Animale, Libourne Cedex, France Author-Name: P Trampus Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: A Csagola Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: T Szalai Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: N Palmai Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: A Toth Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: N Terenyi Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: Z Nagy Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: NA Szeplaki Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: G Somogyi Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: T Barna Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: E Rausch Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: Z Penzes Author-Workplace-Name: Ceva-Phylaxia Zrt., Budapest, Hungary Author-Name: M Szaszko Author-Workplace-Name: TargetEx Biosciences Ltd., Dunakeszi, Hungary Author-Name: Z Lorincz Author-Workplace-Name: TargetEx Biosciences Ltd., Dunakeszi, Hungary Title: Efficacy of a new ready-to-use vaccine against PCV-2d and Mycoplasma hyopneumoniae under experimental conditions Abstract: Mycoplasma hyopneumoniae (M. hyo) and porcine circovirus type 2 (PCV-2) are major and widespread swine pathogens, both implicated in the porcine respiratory disease complex, which can lead to significant economic losses for pig producers. PCV-2d is currently the most prevalent genotype. Vaccination against these two pathogens helps mitigate their impact on pig health and performance. The use of ready-to-mix or ready-to-use (RTU) vaccines targeting PCV-2a or PCV-2a/b and M. hyo is a common practice. This study aimed to evaluate the efficacy of a novel RTU vaccine containing PCV-2d and M. hyo antigens under experimental conditions. Several challenge trials were conducted using PCV-2a, PCV-2b, PCV-2d, and M. hyo to assess the level of protection conferred against different PCV-2 genotypes and M. hyo, as well as to determine the duration of protection. This study demonstrated that the bivalent PCV-2/M. hyo vaccine induces both early and long-lasting protection against infections caused by M. hyo and PCV-2. In addition, cross-protection against the three major PCV-2 genotypes was confirmed. Keywords: enzootic pneumonia, PCV-2 disease, vaccination Journal: Veterinární medicína Pages: 196-202 Volume: 70 Issue: 6 Year: 2025 DOI: 10.17221/6/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/6/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202506-0003.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:6:id:6-2025-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: K Zelaya Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: JH Han Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: J Kim Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: SY Ahn Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: YD Suh Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: DN Lee Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Author-Name: SC Yeon Author-Workplace-Name: Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Korea Title: Application of cold atmospheric microwave plasma on four domestic pigeons (Columba livia domestica) with open wounds Abstract: This paper reports the feasibility of cold atmospheric microwave plasma (CAMP) therapy for birds with open wounds. Four domestic pigeons (Columba livia domestica) with open wounds of varying severity were treated with CAMP as an adjunct to conventional therapy. Wound healing was assessed using a modified scoring system during each treatment session, and the extent of healing was calculated as a percentage. The results revealed variability in wound improvement across cases, influenced by the initial severity of the wounds. In some cases, the outcomes were limited due to underlying conditions that overrode the recovery process, suggesting that the extent of healing may depend more on the initial wound condition than the treatment itself. Nevertheless, other cases showed positive results in healing and recovery under CAMP therapy, highlighting its potential benefits. No adverse reactions or complications were encountered, supporting its safety for avian wound management. These findings suggest that although CAMP can potentially promote wound healing, further studies will be needed to establish standardised treatment protocols. Keywords: avian, plasma medicine, wildlife, wound healing Journal: Veterinární medicína Pages: 218-225 Volume: 70 Issue: 6 Year: 2025 DOI: 10.17221/13/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/13/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202506-0004.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:6:id:13-2025-VETMED