Template-Type: ReDIF-Article 1.0 Author-Name: AA Khedr Author-Workplace-Name: Department of Parasitology, Faculty of Veterinary Medicine, New Valley University, New Valley, Egypt Author-Workplace-Name: Parasitology Laboratory, Department of Bioscience, Durham University, Durham, United Kingdom Author-Name: SM AbdelRaheem Author-Workplace-Name: Department of Public Health, College of Veterinary Medicine, King Faisal University, Al-Hofuf, Al-Ahsa, Saudi Arabia Author-Name: MM Farghaly Author-Workplace-Name: Department of Animal Production, Faculty of Agriculture, Assiut University, Assiut, Egypt Author-Name: SI Alsultan Author-Workplace-Name: Department of Public Health, College of Veterinary Medicine, King Faisal University, Al-Hofuf, Al-Ahsa, Saudi Arabia Author-Name: M Abdulmohsen Author-Workplace-Name: Department of Public Health, College of Veterinary Medicine, King Faisal University, Al-Hofuf, Al-Ahsa, Saudi Arabia Author-Name: S Fathi El-Hawari Author-Workplace-Name: Department of Clinical Science, College of Veterinary Medicine, King Faisal University, Al-Hofuf, Al-Ahsa, Saudi Arabia Author-Name: WG El-Dein Mahmoud Author-Workplace-Name: Parasitology Laboratory, Department of Bioscience, Durham University, Durham, United Kingdom Title: Epidemiological insights into bovine helminthiasis in Upper Egypt: Prevalence, risk factors, and pathological findings Abstract: This study examines the prevalence of helminthic infestations, risk factors, and odds ratios in 1 300 cattle, revealing significant patterns in parasite distribution and influencing factors. Overall, 60.3% of cattle were infested with one or more types of parasites, with Moniezia spp. being the most prevalent (46.9%), followed by Fasciola spp. (36.9%), Paramphistomum spp. (26.8%), and Avitellina spp. (10.8%). Among the seasons, winter exhibited the highest infestation rate (66.1%), and calves under one year of age were more commonly infested (64.2%) than older cattle (over three years: 51.1%, OR = 0.584 1). Distinct seasonal and age-related patterns were observed for specific parasites. Fasciola spp. was most prevalent in winter (45.09%) and among the youngest cattle (47.87%), while Paramphistomum spp. and Moniezia spp. showed less variation across seasons. Avitellina spp. had the lowest infestation rates in the spring, and cattle older than three years were affected. Co-infections were common, notably between Fasciola and other parasites, with the highest co-infestation rate observed between Avitellina spp. and Moniezia spp. Analysis of deworming efficacy indicated higher treatment success for Fasciola spp. and Paramphistomum spp., lower odds of response for Avitellina spp., and no significant treatment effect for Moniezia spp. Microscopic and pathological examinations were also conducted. These results demonstrate the necessity of thorough deworming procedures along with targeted parasite control to reduce significant health hazards in cattle populations. Keywords: cattle, deworming efficacy, helminthic infestations, microscopic analysis, pathological examination Journal: Veterinární medicína Pages: 339-357 Volume: 70 Issue: 10 Year: 2025 DOI: 10.17221/112/2024-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/112/2024-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202510-0001.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:10:id:112-2024-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: M Gultekin Author-Workplace-Name: Department of Biochemistry, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkiye Author-Name: M Eren Author-Workplace-Name: Department of Biochemistry, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkiye Author-Name: FD Koca Author-Workplace-Name: Department of Aquatic Animal and Diseases, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkiye Author-Name: CK Bozbek Author-Workplace-Name: Department of Biochemistry, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkiye Author-Name: N Develi Author-Workplace-Name: Graduate School of Health Science, Erciyes University, Kayseri, Turkiye Title: The effects of zinc oxide nanoparticles on the oxidative stress, caspase-3, cytokine and immunity in rats Abstract: This study was conducted to examine the effects of zinc oxide nanoparticles (ZnO NPs) on the malondialdehyde (MDA) concentrations, superoxidase dismutase (SOD), glutathione peroxidase (GPx) and caspase-3 (CASP3) activities, tumour necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), immunoglobulin (Ig) E, G, M and zinc (Zn) concentrations in the serum/plasma and liver tissues of rats. Forty Wistar Albino rats were separated into five equal groups as the control, 5 and 10 mg/kg, b.w./day ZnO, 5 and 10 mg/kg b.w./day ZnO NPs were administered i.p. every other day for 14 days. The plasma MDA and plasma/liver TNF-α concentrations increased in the 10 mg/kg ZnO, 5 and 10 mg/kg ZnO NPs groups. The plasma SOD, CASP3, plasma/liver GPx activities and serum Zn concentrations increased in all the Zn groups. The highest SOD, GPx and CASP3 activities were detected in the 5 mg/kg ZnO NPs group. The plasma IgG concentrations increased, especially in the ZnO NPs groups. The study findings suggest that 5 mg/kg ZnO NPs could potentially have an ameliorative effect on the possible adverse effects of oxidative stress. These nanoparticles demonstrate their ability to combat oxidative stress by increasing the plasma/tissue SOD, GPx, and CASP3 activities, TNF-α, and IgG concentrations. However, the effectiveness of the nanoparticles may vary depending on the synthesis method, application time, and concentration. Keywords: caspase-3, cytokine, immunoglobulin, oxidative stress, zinc oxide nanoparticles Journal: Veterinární medicína Pages: 379-392 Volume: 70 Issue: 10 Year: 2025 DOI: 10.17221/11/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/11/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202510-0002.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:10:id:11-2025-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: A Cortu Author-Workplace-Name: Department of Veterinary Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkiye Author-Name: O Gungor Author-Workplace-Name: Department of Veterinary Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkiye Title: Effect of trace mineral injection on serum trace mineral concentrations and reproductive indicators in sheep synchronised during the anoestrus period Abstract: Sheep production represents an important source of income for farmers in Türkiye; however, reproductive inefficiencies during the anoestrus period pose a major challenge to productivity. This study aimed to evaluate the effects of injectable trace minerals (copper, selenium, manganese, and zinc) on the reproductive performance of Awassi ewes synchronised during the anoestrous period. A total of 200 clinically healthy ewes were randomly allocated to two groups: the trace mineral group (TRACE, n = 100), which received 2 ml of a trace mineral solution 14 days before oestrus synchronisation, and the control group (CON, n = 100), which received 2 ml of 0.9% NaCl. Oestrus was synchronised using intravaginal sponges containing 60 mg medroxyprogesterone acetate for 12 days, followed by administration of 500 IU equine chorionic gonadotrophin at sponge removal. Ewes were hand-mated for five days following synchronisation. Variables assessed included serum trace mineral concentrations, response to synchronisation, and reproductive outcomes (oestrus rate, pregnancy rate, lambing rate, incidence of multiple births, and dystocia). No significant differences (P > 0.05) were found between groups in serum concentrations of copper, zinc, or manganese. Although the duration of oestrus was significantly longer in the TRACE group compared to control (29.66 ± 0.96 h vs 26.09 ± 0.89 h; P = 0.006), all other reproductive indicators were similar between groups. These findings suggest that a single pre-synchronisation injection of trace minerals does not significantly improve the reproductive performance or mineral status in anoestrous Awassi ewes. Further research is needed to determine the optimal timing and dosing strategies for supplementing trace minerals in sheep. Keywords: ewe, mineral, oestrus, pregnancy, trace element Journal: Veterinární medicína Pages: 358-368 Volume: 70 Issue: 10 Year: 2025 DOI: 10.17221/28/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/28/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202510-0003.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:10:id:28-2025-VETMED Template-Type: ReDIF-Article 1.0 Author-Name: SK Slunsky Author-Workplace-Name: Neurological Department, Small Animal Hospital, AniCura Tierklinik Haar, Haar, Bavaria, Germany Author-Name: P Slunsky Author-Workplace-Name: Department of Surgery and Orthopaedics, Faculty of Veterinary Medicine, University of Veterinary Sciences Brno, Brno, Czech Republic Author-Name: E Fort Author-Workplace-Name: Joint Research Unit for Epidemiology and Translational Surveillance, Claude Bernard University Lyon, Villeurbanne, France Author-Name: L Brunnberg Author-Workplace-Name: Department of Veterinary Medicine, Small Animal Clinic, Freie Universität Berlin, Berlin, Germany Title: Prevalence of lumbosacral transitional vertebrae and association with hip dysplasia in Rhodesian Ridgebacks in Germany Abstract: Congenital anomalies affecting the spinal column are frequently observed in certain dog breeds. One such condition occurs at the junction between the lower back and the sacrum, where vertebrae exhibit mixed structural characteristics. This retrospective study analysed imaging records of Rhodesian Ridgebacks collected over 28 years, selecting only those that met strict positioning standards for evaluation. A total of 2 012 cases were analysed using established classification methods, identifying three distinct structural variations: a typical junction, a bilaterally altered morphology, and an asymmetrical form affecting one side. The prevalence of these variations was 7.4%, with symmetrical alterations found in 5% of cases and asymmetrical alterations in 2.4%. Statistical analysis did not reveal a significant association between these anatomical variations and canine hip dysplasia (CHD) (P = 0.170 0). These findings support previous research indicating that there is no direct link between these structural variations and joint disorders in this breed. The study represents the most extensive investigation of its kind in this canine population, highlighting that such vertebral variations are frequently observed in routine radiographic screenings, but despite decades of research, consistent clinical correlations remain elusive - underscoring the need for further systematic investigation. Keywords: breed-specific conditions, canine orthopaedics, imaging diagnostics, musculoskeletal research, spinal malformations, vertebral classification Journal: Veterinární medicína Pages: 369-378 Volume: 70 Issue: 10 Year: 2025 DOI: 10.17221/30/2025-VETMED File-URL: http://vetmed.agriculturejournals.cz/doi/10.17221/30/2025-VETMED.html File-Format: text/html X-File-Ref: http://agriculturejournals.cz/RePEc/caa/references/vet-202510-0004.txt Handle: RePEc:caa:jnlvet:v:70:y:2025:i:10:id:30-2025-VETMED