Czech J. Food Sci., 2004, 22(10):S73-S75 | DOI: 10.17221/10615-CJFS

Synthesis of (Z,Z)-octadeca-10,12-dienoic acid

C. Kellersmann, W. Francke, H. Steinhart
Department of Food Chemistry, Institute of Biochemistry and Food Chemistry,
1 University of Hamburg, Hamburg, Germany, *E-mail: carolin_kellersmann@gmx.de;
2 Institute of Organic Chemistry, University of Hamburg, Hamburg, Germany

(Z,Z)-Octadeca-10,12-dienoic acid was synthesised by coupling (Z)-1-bromohept-1-ene with protected undec-10-yne-1-ol. Stereoselective hydrogenation of the triple bond of the obtained enyne-system followed by deprotection yielded (Z,ZZ)-octadeca-10,12-dienol. The latter can be easily oxidized to the corresponding acid.

Keywords: synthesis of conjugated linoleic acid; CLA; stereoselective hydrogenation

Published: December 31, 2004  Show citation

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Kellersmann C, Francke W, Steinhart H. Synthesis of (Z,Z)-octadeca-10,12-dienoic acid. Czech J. Food Sci. 2004;22(Special Issue):S73-75. doi: 10.17221/10615-CJFS.
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