Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken
S. Arva, M. Zendehdel, Y. EbrahimNezhad, J. Ghiasi Ghalehkandi, S. Hassanpour, H. Aghdam Shahryarhttps://doi.org/10.17221/2/2016-CJASCitation:Arva S., Zendehdel M., EbrahimNezhad Y., Ghiasi Ghalehkandi J., Hassanpour S., Aghdam Shahryar H. (2017): Effect of opioid receptors agonists on feeding behaviour using different diets in ad libitum fed neonatal chicken. Czech J. Anim. Sci., 62: 98-109.
Despite progress in studying the role of opioids in reward, the effect of opioid receptors on feeding behaviour in ad libitum fed meat-type chicken offered different diet types is still unclear. So in this study, 12 experiments (each included 4 groups) were designed to determine the role of μ, δ, and κ receptors with different diets on feeding responses in ad libitum fed neonatal chicken. In Experiment 1, group A chicken were intracerebroventricularly (ICV) injected with saline, groups B–D chicken were ICV injected with DAMGO (µ-opioid receptor agonist; 125, 250, and 500 pmol), then standard diet without fat was offered. In Experiment 2, group A chicken were ICV injected with saline, groups B–D chicken were ICV injected with DAMGO (125, 250, and 500 pmol) and diet with nutrient energy ratio 20% below standard was provided to the birds. Experiments 3–4 were similar to Experiment 1, except after injection, diets containing nutrient energy ratio 20% above standard and standard diet with fat were provided to the birds, respectively. In Experiment 5, chicken were ICV injected with saline, DPDPE (δ-opioid receptor agonist) at doses of 20, 40, and 80 nmol, and then received standard diet without fat. Experiments 6–8 were similar to Experiment 5 in which diet containing nutrient energy ratio by 20% lower than standard, diet containing nutrient energy ratio by 20% higher than standard, and diet containing fat were provided instead of standard diet without fat to the birds, respectively. In Experiment 9, birds received ICV injection of saline and U-50488H (κ-opioid receptor agonist; 10, 20, and 40 nmol) and were provided standard diet without fat. Experiments 10–12 were similar to Experiment 9 but after ICV injection, birds were fed diet containing by 20% lower nutrient energy ratio, diet containing by 20% higher nutrient energy ratio, and standard diet containing fat, respectively. Then the cumulative food intake was measured until 180 min post injection. According to the results, DAMGO decreased while DPDPE and U-50488H increased the food intake (P < 0.05). These findings suggest endogenous governing food preferences via δ- and κ-opioid receptor in ad libitum fed neonatal chicken.Keywords:
appetite; food selection; central food intake regulation; meat-type chickenReferences:
Barnes Maria J., Holmes Gregory, Primeaux Stefany D., York David A., Bray George A. (2006): Increased expression of mu opioid receptors in animals susceptible to diet-induced obesity. Peptides, 27, 3292-3298 https://doi.org/10.1016/j.peptides.2006.08.008Bodnar Richard J. (2014): Endogenous opiates and behavior: 2013. Peptides, 62, 67-136 https://doi.org/10.1016/j.peptides.2014.09.013Boghossian Stéphane, Jourdan Didier, Dacher Matthieu, Alliot Josette (2001): Effect of morphine on caloric intake and macronutrient selection in male and female Lou/c/jall rats during ageing. Mechanisms of Ageing and Development, 122, 1825-1839 https://doi.org/10.1016/S0047-6374(01)00321-9Bungo Takashi, Kawamura Kazuya, Izumi Tomofumi, Dodo Koh-Ichi, Ueda Hiroshi (2004): Feeding responses to μ-, δ- and κ-opioid receptor agonists in the meat-type chick. Pharmacology Biochemistry and Behavior, 78, 707-710 https://doi.org/10.1016/j.pbb.2004.05.015Bungo Takashi, Dodo Koh-Ichi, Kawamura Kazuya, Izumi Tomofumi, Ueda Hiroshi (2005): Effects of various μ- and δ-opioid ligands on food intake in the meat-type chick. Physiology & Behavior, 85, 519-523 https://doi.org/10.1016/j.physbeh.2005.05.015Davis Joel L., Masuoka David T., Gerbrandt Lauren K., Cherkin Arthur (1979): Autoradiographic distribution of L-proline in chicks after intracerebral injection. Physiology & Behavior, 22, 693-695 https://doi.org/10.1016/0031-9384(79)90233-6Dodo Koh-Ichi, Izumi Tomofumi, Ueda Hiroshi, Bungo Takashi (2005): Response of neuropeptide Y-induced feeding to μ-, δ- and κ-opioid receptor antagonists in the neonatal chick. Neuroscience Letters, 373, 85-88 https://doi.org/10.1016/j.neulet.2004.09.065Figlewicz Dianne P., Sipols Alfred J. (2010): Energy regulatory signals and food reward. Pharmacology Biochemistry and Behavior, 97, 15-24 https://doi.org/10.1016/j.pbb.2010.03.002Furuse Mitsuhiro, Matsumoto Megumi, Saito Noboru, Sugahara Kunio, Hasegawa Shin (1997): The central corticotropin-releasing factor and glucagon-like peptide-1 in food intake of the neonatal chick. European Journal of Pharmacology, 339, 211-213 https://doi.org/10.1016/S0014-2999(97)01391-5Furuse M., Ando R., Bungo T., Shimojo M., Masuda Y. (1999): Intracerebroventricular injection of orexins does not stimulate food intake in neonatal chicks. British Poultry Science, 40, 698-700 https://doi.org/10.1080/00071669987115Gosnell B A, Levine A S (2009): Reward systems and food intake: role of opioids. International Journal of Obesity, 33, S54-S58 https://doi.org/10.1038/ijo.2009.73Haghighi A, Melka M G, Bernard M, Abrahamowicz M, Leonard G T, Richer L, Perron M, Veillette S, Xu C J, Greenwood C M T, Dias A, El-Sohemy A, Gaudet D, Paus T, Pausova Z (): Opioid receptor mu 1 gene, fat intake and obesity in adolescence. Molecular Psychiatry, 19, 63-68 https://doi.org/10.1038/mp.2012.179Hassanpour S., Zendehdel M., Babapour V., Charkhkar S. (): Endocannabinoid and nitric oxide interaction mediates food intake in neonatal chicken. British Poultry Science, 56, 443-451 https://doi.org/10.1080/00071668.2015.1059407Kaneko Kentaro, Yoshikawa Masaaki, Ohinata Kousaku (2012): Novel orexigenic pathway prostaglandin D2–NPY system – Involvement in orally active orexigenic δ opioid peptide. Neuropeptides, 46, 353-357 https://doi.org/10.1016/j.npep.2012.10.003Khan Md. Sakirul Islam, Ohkubo Takeshi, Masuda Naoto, Tachibana Tetsuya, Ueda Hiroshi (2009): Central administration of metastin increases food intake through opioid neurons in chicks. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 153, 209-212 https://doi.org/10.1016/j.cbpa.2009.02.013Kozlov Andrey P., Nizhnikov Michael E., Kramskaya Tatiana A., Varlinskaya Elena I., Spear Norman E. (2013): Mu-opioid blockade reduces ethanol effects on intake and behavior of the infant rat during short-term but not long-term social isolation. Pharmacology Biochemistry and Behavior, 103, 773-782 https://doi.org/10.1016/j.pbb.2012.11.008Le Merrer J., Becker J. A. J., Befort K., Kieffer B. L. (): Reward Processing by the Opioid System in the Brain. Physiological Reviews, 89, 1379-1412 https://doi.org/10.1152/physrev.00005.2009Naleid A. M., Grace M. K., Chimukangara M., Billington C. J., Levine A. S. (2007): Paraventricular opioids alter intake of high-fat but not high-sucrose diet depending on diet preference in a binge model of feeding. AJP: Regulatory, Integrative and Comparative Physiology, 293, R99-R105 https://doi.org/10.1152/ajpregu.00675.2006Novoseletsky Nataly, Nussinovitch Amos, Friedman-Einat Miriam (2011): Attenuation of food intake in chicks by an inverse agonist of cannabinoid receptor 1 administered by either injection or ingestion in hydrocolloid carriers. General and Comparative Endocrinology, 170, 522-527 https://doi.org/10.1016/j.ygcen.2010.11.011. H.A. Olanrewaju, . J.P. Thaxton, . W.A. Dozier III, . J. Purswell, . W.B. Roush, . S.L. Branton (2006): A Review of Lighting Programs for Broiler Production. International Journal of Poultry Science, 5, 301-308 https://doi.org/10.3923/ijps.2006.301.308Olszewski P.K., Alsio J., Schioth H.B., Levine A.S. (2011): Opioids as facilitators of feeding: Can any food be rewarding? Physiology and Behavior, 104, 105–110.Parker Kyle E., Johns Howard W., Floros Ted G., Will Matthew J. (2014): Central amygdala opioid transmission is necessary for increased high-fat intake following 24-h food deprivation, but not following intra-accumbens opioid administration. Behavioural Brain Research, 260, 131-138 https://doi.org/10.1016/j.bbr.2013.11.014Peciña Susana (2008): Opioid reward ‘liking’ and ‘wanting’ in the nucleus accumbens. Physiology & Behavior, 94, 675-680 https://doi.org/10.1016/j.physbeh.2008.04.006Saito Ei-Suke, Kaiya Hiroyuki, Tachibana Tetsuya, Tomonaga Shozo, Denbow D. Michel, Kangawa Kenji, Furuse Mitsuhiro (2005): Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory Peptides, 125, 201-208 https://doi.org/10.1016/j.regpep.2004.09.003Shiraishi Jun-ichi, Yanagita Kouchi, Fujita Masanori, Bungo Takashi (2008): μ-Opioid receptor agonist diminishes POMC gene expression and anorexia by central insulin in neonatal chicks. Neuroscience Letters, 439, 227-229 https://doi.org/10.1016/j.neulet.2008.05.040Shojaei M., Zendehdel M., Babapour V., Charkhkar S., Hassanpour S. (): Opioid-induced hypophagia is mediated by 5-HT<sub>2</sub>c receptors in neonatal layer-type chicken. Czech Journal of Animal Science, 60, 400-410 https://doi.org/10.17221/8458-CJASSteinman Judith L., Fujikawa Denson G., Wasterlain Claude G., Cherkin Arthur, Morley John E. (1987): The effects of adrenergic, opioid and pancreatic polypeptidergic compounds on feeding and other behaviors in neonatal leghorn chicks. Peptides, 8, 585-592 https://doi.org/10.1016/0196-9781(87)90029-5Taha Sharif A. (2010): Preference or fat? Revisiting opioid effects on food intake. Physiology & Behavior, 100, 429-437 https://doi.org/10.1016/j.physbeh.2010.02.027van Tienhoven A., Juh�sz L. P. (1962): The chicken telencephalon, diencephalon and mesencephalon in stereotaxic coordinates. The Journal of Comparative Neurology, 118, 185-197 https://doi.org/10.1002/cne.901180205Woolley J.D., Lee B.S., Fields H.L. (2006): Nucleus accumbens opioids regulate flavor-based preferences in food consumption. Neuroscience, 143, 309-317 https://doi.org/10.1016/j.neuroscience.2006.06.067Zendehdel Morteza, Hassanpour Shahin (): Ghrelin-induced hypophagia is mediated by the β2 adrenergic receptor in chicken. The Journal of Physiological Sciences, , - https://doi.org/10.1007/s12576-014-0330-yZendehdel M., Baghbanzadeh A., Yeganeh B., Hassanpour S. (2015a): The role of cyclooxygenase inhibitors in lipopolysaccharide-induced hypophagia in chicken. Czech Journal of Animal Science, 60, 342–350.Zendehdel M., Ghashghayi E., Hassanpour S., Baghbanzadeh A., Jonaidi H. (2015b): Interaction between opioidergic and dopaminergic systems on food intake in neonatal layer type chicken. International Journal of Peptide Research and Therapeutics, 22, 83–92.Zendehdel M., Hassanpour S., Babapour V., Charkhkar S., Mahdavi M. (2015c): Interaction between endocannabinoid and opioidergic systems regulates food intake in neonatal chicken. International Journal of Peptide Research and Therapeutics, 21, 289–297.Zhang M., Gosnell B.A., Kelley A.E. (1998): Intake of high-fat food is selectively enhanced by mu opioid receptor stimulation within the nucleus accumbens. Journal of Pharmacology and Experimental Therapeutics, 285, 908–914.Zheng H., Patterson L. M., Berthoud H.-R. (2007): Orexin Signaling in the Ventral Tegmental Area Is Required for High-Fat Appetite Induced by Opioid Stimulation of the Nucleus Accumbens. Journal of Neuroscience, 27, 11075-11082 https://doi.org/10.1523/JNEUROSCI.3542-07.2007