Free amino acid concentration in serum and trapezius muscle from male and female silver foxes (Vulpes vulpes)
Iwona Łuszczewska-Sierakowska, Marcin R. Tatara, Maria Szpetnar, Jacek Kurzepa
https://doi.org/10.17221/42/2018-CJASCitation:Łuszczewska-Sierakowska I., Tatara M.R., Szpetnar M., Kurzepa J. (2019): Free amino acid concentration in serum and trapezius muscle from male and female silver foxes (Vulpes vulpes). Czech J. Anim. Sci., 64: 130-140.Serum and muscle concentrations of 29 amino acids were determined in Silver fox. Serum concentrations of proline, alanine, tyrosine and aromatic amino acids were significantly higher in males than in females (all P = 0.05). Taurine and glycine concentrations in skeletal muscles were significantly higher in males than in females (P < 0.01). Muscle concentrations of cysteic acid, taurine, aspartate, threonine, serine, glycine, alanine, citruline, valine, leucine, gamma-amino-butyrate, ethanoloamine, lysine and histidine were significantly higher than in serum in both sexes (P < 0.05). In females, the concentrations of glutamate, glutamine, cystathionine, isoleucine, tyrosine, phenylalanine, arginine and amino-adipic acid were significantly higher in muscles than in serum (P < 0.05). Tryptophan concentration was significantly higher in serum from males than in muscles (P = 0.01). The concentration of branched-chain amino acids in skeletal muscles was approximately two times higher than in serum in both groups of foxes (P ≤ 0.01). Similar differences were obtained for aromatic amino acids in females (P = 0.04). The elaborated experimental model may serve for further studies focused on amino acid metabolism regulation in Canide and other monogastric mammals, especially with the use of environmental, dietary, pharmacological and toxicological factors. The elaborated experimental model may be an attractive alternative to replace some experiments on dogs.
amino acids; animal model; ion-exchange chromatography; Carnivora; predator
References:Arciero P. J., Goran M. I., Poehlman E. T. (1993): Resting metabolic rate is lower in women than in men. Journal of Applied Physiology, 75, 2514-2520 https://doi.org/10.1152/jappl.1993.75.6.2514 ASKANAZI J., FURST P., MICHELSEN C. B., ELWYN D. H., VINNARS E., GUMP F. E., STINCHFIELD F. E., KINNEY J. M. (1980): Muscle and Plasma Amino Acids after Injury. Annals of Surgery, 191, 465-472 https://doi.org/10.1097/00000658-198004000-00013 Bellance Nadège, Pabst Lisa, Allen Genevara, Rossignol Rodrigue, Nagrath Deepak (2012): Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1817, 2060-2071 https://doi.org/10.1016/j.bbabio.2012.07.004 Canepa Alberto, Filho José Carolino Divino, Gutierrez Alberto, Carrea Alba, Forsberg Ann‐Marie, Nilsson Eva, Verrina Enrico, Perfumo Francesco, Bergström Jonas (2002): Free amino acids in plasma, red blood cells, polymorphonuclear leukocytes, and muscle in normal and uraemic children. Nephrology Dialysis Transplantation, 17, 413-421 https://doi.org/10.1093/ndt/17.3.413
Chmielowiec K., Tatara M.R., Krupski W., Luszczewska-Sierakowska I., Bienko M., Szabelska A., Jakubczak A., Kostro K. (2014): Sex-related differences of morphometric and densitometric properties of lumbar vertebrae in silver foxes (Vulpes vulpes). Bone Abstracts, 3, PP44. Curis Emmanuel, Crenn Pascal, Cynober Luc (2007): Citrulline and the gut. Current Opinion in Clinical Nutrition and Metabolic Care, 10, 620-626 https://doi.org/10.1097/MCO.0b013e32829fb38d
Field C.J., Johnson I.R., Schley P.D. (2002): Nutrients and their role in host resistance to infection. Journal of Leukocyte Biology, 71, 16–32. Filho J.C. Divino, Bergström J., Stehle P., Fürst P. (1997): Simultaneous measurements of free amino acid patternsof plasma, muscle and erythrocytes in healthy human subjects. Clinical Nutrition, 16, 299-305 https://doi.org/10.1016/S0261-5614(97)80015-5
Flynn J.J. (1998): Early Cenozoic Carnivora (“Miacoidea”). In: Janis C.M., Scott K.M., Jacobs L.L. (eds): Evolution of Tertiary Mammals of North America. Cambridge University Press, Cambridge, UK, 110–123. Flynn N E, Knabe D A, Mallick B K, Wu G (2000): Postnatal changes of plasma amino acids in suckling pigs.. Journal of Animal Science, 78, 2369- https://doi.org/10.2527/2000.7892369x Flynn Nick E., Bird Jared G., Guthrie Aaron S. (2009): Glucocorticoid regulation of amino acid and polyamine metabolism in the small intestine. Amino Acids, 37, 123-129 https://doi.org/10.1007/s00726-008-0206-7
Fraga Fuentes M.D., de Juana Velasco P., Pintor Recuenco R. (1996): Metabolic role of glutamine and its importance in nutritional therapy. Nutrición Hospitalaria, 11, 215–225. García F. J., Pons A., Alemany M., Palou A. (2007): Sex differences in blood amino acid concentration and cell/plasma distribution in the domestic fowl. British Poultry Science, 27, 379-384 https://doi.org/10.1080/00071668608416893 Gołyński Marcin, Szpetnar Maria, Tatara Marcin R., Lutnicki Krzysztof, Gołyńska Magdalena, Kurek Łukasz, Szczepanik Marcin, Wilkołek Piotr (2016): Content of selected amino acids in the gastrocnemius muscle during experimental hypothyroidism in rats. Journal of Veterinary Research, 60, 489-493 https://doi.org/10.1515/jvetres-2016-0072 Hammarqvist Folke, Angsten Gertrud, Meurling Staffan, Andersson Kerstin, Wernerman Jan (2010): Age-related changes of muscle and plasma amino acids in healthy children. Amino Acids, 39, 359-366 https://doi.org/10.1007/s00726-009-0446-1 Hou Yongqing, Yin Yulong, Wu Guoyao (2015): Dietary essentiality of “nutritionally non-essential amino acids” for animals and humans. Experimental Biology and Medicine, 240, 997-1007 https://doi.org/10.1177/1535370215587913 Jing Xi, Farberg Aaron, Monson Laura, Donneys Alexis, Tchanque-Fossuo Catherine, Buchman Steven (2012): Radiomorphometric Quantitative Analysis of Vasculature Utilizing Micro–Computed Tomography and Vessel Perfusion in the Murine Mandible. Craniomaxillofacial Trauma and Reconstruction, 05, 223-230 https://doi.org/10.1055/s-0032-1329540 Kidawa Dorota, Kowalczyk Rafał (2011): The effects of sex, age, season and habitat on diet of the red fox Vulpes vulpes in northeastern Poland. Acta Theriologica, 56, 209-218 https://doi.org/10.1007/s13364-011-0031-3 Kittleson Mark D., Keene Bruce, Pion Paul D., Loyer Carroll G. (1997): Results of the Multicenter Spaniel Trial (MUST): Taurine-and Carnitine-Responsive Dilated Cardiomyopathy in American Cocker Spaniels With Decreased Plasma Taurine Concentration. Journal of Veterinary Internal Medicine, 11, 204-211 https://doi.org/10.1111/j.1939-1676.1997.tb00092.x Lanocha Natalia, Kalisinska Elzbieta, Kosik-Bogacka Danuta I., Budis Halina, Noga-Deren Kinga (2012): Trace metals and micronutrients in bone tissues of the red fox Vulpes vulpes (L., 1758). Acta Theriologica, 57, 233-244 https://doi.org/10.1007/s13364-012-0073-1 Lu Weifeng, Dong Zhihui, Liu Zhenjie, Fu Weiguo, Peng Yifeng, Chen Shaoliang, Xiao Tiqiao, Xie Honglan, Du Guohao, Deng Biao, Zhang Xiangman (2010): Detection of Microvasculature in Rat Hind Limb Using Synchrotron Radiation. Journal of Surgical Research, 164, e193-e199 https://doi.org/10.1016/j.jss.2010.05.015 MacLennan Peter A., Brown R.A., Rennie Michael J. (1987): A positive relationship between protein synthetic rate and intracellular glutamine concentration in perfused rat skeletal muscle. FEBS Letters, 215, 187-191 https://doi.org/10.1016/0014-5793(87)80139-4 MacLennan Peter A., Smith Kenneth, Weryk Brian, Watt Peter W., Rennie Michael J. (1988): Inhibition of protein breakdown by glutamine in perfused rat skeletal muscle. FEBS Letters, 237, 133-136 https://doi.org/10.1016/0014-5793(88)80186-8 Manso Filho Hélio C., Costa Helena E., Wu Guoyao, McKeever Kenneth H., Watford Malcolm (2009): Equine placenta expresses glutamine synthetase. Veterinary Research Communications, 33, 175-182 https://doi.org/10.1007/s11259-008-9167-2 Moise N.Sydney, Pacioretty Linda M., Kallfelz Francis A., Stipanuk Martha H., King John M., Gilmour Robert F. (1991): Dietary taurine deficiency and dilated cardiomyopathy in the fox. American Heart Journal, 121, 541-547 https://doi.org/10.1016/0002-8703(91)90724-V Montanari Alberto, Simoni Isabella, Vallisa Daniele, Trifirò Antonio, Colla Rossana, Abbiati Roberto, Borghi Loris, Novarini Almerico (1988): Free amino acids in plasma and skeletal muscle of patients with liver cirrhosis. Hepatology, 8, 1034-1039 https://doi.org/10.1002/hep.1840080509 Perła-Kaján J., Twardowski T., Jakubowski H. (2007): Mechanisms of homocysteine toxicity in humans. Amino Acids, 32, 561-572 https://doi.org/10.1007/s00726-006-0432-9 Pion P., Kittleson M., Rogers Q., Morris J. (1987): Myocardial failure in cats associated with low plasma taurine: a reversible cardiomyopathy. Science, 237, 764-768 https://doi.org/10.1126/science.3616607 Piotrowska Anna, Szymeczko Roman, Ozgo Małgorzata, Bogusławska-Tryk Monika, Burlikowska Katarzyna (2008): Morphological and Mineral Characteristics of Peripheral Blood in Female Polar Fox in Relation to Age. Folia Biologica, 56, 263-267 https://doi.org/10.3409/fb.56_3-4.263-267 Pitkanen H. T., Oja S. S., Kemppainen K., Seppa J. M., Mero A. A. (2003): Serum amino acid concentrations in aging men and women. Amino Acids, 24, 413-421 https://doi.org/10.1007/s00726-002-0338-0
Schaffer S.W., Jong C.J., Ramila K.C., Azuma J. (2010): Physiological roles of taurine in heart and muscle. Journal of Biomedical Science, 17 (Suppl. 1), S2. Seibert Ryan, Abbasi Fahim, Hantash Feras M., Caulfield Michael P., Reaven Gerald, Kim Sun H. (2015): Relationship between insulin resistance and amino acids in women and men. Physiological Reports, 3, e12392- https://doi.org/10.14814/phy2.12392
Sikorska H., Cianciara J., Wiercinska-Drapalo A. (2010): Physiological functions of L-ornithine and L-aspartate in the body and the efficacy of administration of L-ornithine-L-aspartate in conditions of relative deficiency. Polski Merkuriusz Lekarski, 28, 490–495. STINNETT J. DWIGHT, ALEXANDER J. WESLEY, WATANABE CHIYUKI, MACMILLAN BRUCE G., FISCHER JOSEF E., MORRIS MICHAEL J., TROCKI ORRAWIN, MISKELL PHILLIP, EDWARDS LAURA, JAMES HOWARD (1982): Plasma and Skeletal Muscle Amino Acids Following Severe Burn Injury in Patients and Experimental Animals. Annals of Surgery, 195, 75-89 https://doi.org/10.1097/00000658-198201001-00012 Takeshita Satoshi, Isshiki Takaaki, Mori Hidezo, Tanaka Etsuro, Eto Koji, Miyazawa Yoshimichi, Tanaka Akira, Shinozaki Yoshiro, Hyodo Kazuyuki, Ando Masami, Kubota Misao, Tanioka Kenkichi, Umetani Keiji, Ochiai Masahiko, Sato Tomohide, Miyashita Hideo (1997): Use of Synchrotron Radiation Microangiography to Assess Development of Small Collateral Arteries in a Rat Model of Hindlimb Ischemia. Circulation, 95, 805-808 https://doi.org/10.1161/01.CIR.95.4.805 Tatara Marcin R., Brodzki Adam, Pyz-Lukasik Renata, Pasternak Kazimierz, Szpetnar Maria (2012): Sex-related Differences in Skeletal Muscle Amino Acid Concentrations in 20 Week Old Turkeys. The Journal of Poultry Science, 49, 219-223 https://doi.org/10.2141/jpsa.011099 Tatara MR, Brodzki A., Pasternak K., Szpetnar M., Rosenbeiger P., Tymczyna B., Niedziela D. (2014): Changes of amino acid concentrations in Polish Merino sheep between 21 and 150 days of life. Veterinární Medicína, 59, 68-75 https://doi.org/10.17221/7315-VETMED Tatara Marcin R., Łuszczewska-Sierakowska Iwona, Krupski Witold (2018): Serum Concentration of Macro-, Micro-, and Trace Elements in Silver Fox (Vulpes vulpes) and Their Interrelationships with Morphometric, Densitometric, and Mechanical Properties of the Mandible. Biological Trace Element Research, 185, 98-105 https://doi.org/10.1007/s12011-017-1221-x Van Valkenburgh B. (2007): Deja vu: the evolution of feeding morphologies in the Carnivora. Integrative and Comparative Biology, 47, 147-163 https://doi.org/10.1093/icb/icm016 Viguet-Carrin S., Garnero P., Delmas P. D. (2006): The role of collagen in bone strength. Osteoporosis International, 17, 319-336 https://doi.org/10.1007/s00198-005-2035-9 Wu Guoyao (2009): Amino acids: metabolism, functions, and nutrition. Amino Acids, 37, 1-17 https://doi.org/10.1007/s00726-009-0269-0 Wu G, Thompson J R (1990): The effect of glutamine on protein turnover in chick skeletal muscle in vitro. Biochemical Journal, 265, 593-598 https://doi.org/10.1042/bj2650593 Xi Pengbin (2011): Regulation of protein metabolism by glutamine: implications for nutrition and health. Frontiers in Bioscience, 16, 578- https://doi.org/10.2741/3707
Zhan Y.M., Yasuda J., Too K. (1991): Reference data on the anatomy and serum biochemistry of the silver fox. Japanese Journal of Veterinary Research, 39, 39–50.
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