Induction of accessory corpus luteum by gonadorelin in relation to the time of treatment and the follicle size in inseminated cowsžel R., Chambert C., Musilová D., Čech S., Páleník T. (2017): Induction of accessory corpus luteum by gonadorelin in relation to the time of treatment and the follicle size in inseminated cows. Czech J. Anim. Sci., 62: 195-200.
download PDF
This study evaluated the occurrence of two corpora lutea (CL) and the pregnancy rate in cows treated with gonadorelin on days 5, 6 or 7 after insemination in relation to the day of treatment and the size of the largest follicle on the ovaries at the time of treatment. Cows bearing one CL on days 5 (n = 40), 6 (n = 48), and 7 (n = 47) after insemination with defined size of the largest follicle on the ovaries (small ≤ 9 mm, n = 34; medium 10–14 mm, n = 59; large 15–20 mm, n = 42) were included in the study. Gonadorelin was administered after examination (day 0) and ultrasonographic examination was repeated on days 14, 28, and around day 90. The occurrence of 2 CL vs 1 CL was higher in pregnant cows on day 14 as well as on day 28 (86 vs 14% and 82.5 vs 14%, n = 57). Pregnancy rates on day 28 and around day 90 were higher in cows bearing 2 CL (n = 57) vs cows bearing 1 CL (n = 54) (82.5 vs 18.5% and 79.0 vs 18.5%, P < 0.001). The occurrence of 2 CL on day 28 was higher in cows treated on day 5 compared to cows treated on day 6 or 7 after insemination (60.0 vs 33.3 or 36.2%, P < 0.05). No significant differences in the number of CL and pregnancy rate were found in relation to follicle size at the time of treatment. Our results showed the higher efficiency of accessory CL induction by gonadorelin administration in cows treated on day 5 vs those treated on day 6 or 7 post insemination, however efficiency of the treatment was not influenced by the size of the largest follicle on the ovaries.
Bartolome J.A., Sozzi A., McHale J., Swift K., Kelbert D., Archbald L.F., Thatcher W.W. (2005): Resynchronization of ovulation and timed insemination in lactating dairy cows. Theriogenology, 63, 1643-1658
Bartolome J.A., Kamimura S., Silvestre F., Arteche A.C.M., Trigg T., Thatcher W.W. (2006): The use of a deslorelin implant (GnRH agonist) during the late embryonic period to reduce pregnancy loss. Theriogenology, 65, 1443-1453
Bech-Sàbat G., López-Gatius F., García-Ispierto I., Santolaria J.P., Serrano B., Nogareda C., de Sousa N.M., Beckers J.F., Yániz J. (2009): Pregnancy patterns during the early fetal period in high producing dairy cows treated with GnRH or progesterone. Theriogenology, 71, 920-929
Diskin M.G, Austin E.J, Roche J.F (2002): Exogenous hormonal manipulation of ovarian activity in cattle. Domestic Animal Endocrinology, 23, 211-228
Dolezel R., Bartonek J., Musilova D., Cech S., Palenik T. (2013): Effect of GnRH administration on day 7 after insemination on ovarian activity and pregnancy in dairy cows. Reproduction in Domestic Animals, 48 (Suppl. 1), 109.
Dolezel R., Musilova D., Bartonek J., Cech S., Palenik T. (2014): Factors influencing induction of accessory corpus luteum by GnRH in inseminated cows. Reproduction in Domestic Animals, 49 (Suppl. 3), 64.
Ergene O. (2012): Progesterone concentrations and pregnancy rates of repeat breeder cows following postinsemination PRID and GnRH treatments. Turkish Journal of Veterinary and Animal Sciences, 36, 283–288.
Garcia-Ispierto I, López-Gatius F (2012): Effects of GnRH or Progesterone Treatment on Day 5 Post-AI on Plasma Progesterone, Luteal Blood Flow and Leucocyte Counts During the Luteal Phase in Dairy Cows. Reproduction in Domestic Animals, 47, 224-229
Geary T.W., Downing E.R., Bruemmer J.E., Whittier J.C. (2000): Ovarian and Estrous Response of Suckled Beef Cows to the Select Synch Estrous Synchronization Protocol11This research was supported by a grant from Select Sires. The authors express their appreciation to Select Sires and to Merial, Pharmacia & Upjohn, and DDx, Inc. for their generous donations of Cystorelin, Lutalyse, and HeatWatch, respectively, and to Dave Schutz and Doug Couch at the Eastern Colorado Research Center for assistance in data collection.. The Professional Animal Scientist, 16, 1-5
Humblot P. (2001): Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants. Theriogenology, 56, 1417-1433
Jaiswal R.S., Singh J., Marshall L., Adams G.P. (2009): Repeatability of 2-wave and 3-wave patterns of ovarian follicular development during the bovine estrous cycle. Theriogenology, 72, 81-90
López-Gatius F., Santolaria P., Martino A., Delétang F., De Rensis F. (2006): The effects of GnRH treatment at the time of AI and 12 days later on reproductive performance of high producing dairy cows during the warm season in northeastern Spain. Theriogenology, 65, 820-830
Macmillan K.L., Taufa V.K., Day A.M. (1986): Effects of an agonist of gonadotrophin releasing hormone (Buserelin) in cattle. III. Pregnancy rates after a post-insemination injection during metoestrus or dioestrus. Animal Reproduction Science, 11, 1-10
Martinez M.F., Mapletoft R.J., Kastelic J.P., Carruthers T. (2003): The effects of 3 gonadorelin products on luteinizing hormone release, ovulation, and follicular wave emergence in cattle. Canadian Veterinary Journal, 44, 125–131.
Mehni SB, Shabankareh HK, Kazemi-Bonchenari M, Eghbali M (2012): The Comparison of Treating Holstein Dairy Cows with Progesterone, CIDR and GnRH After Insemination on Serum Progesterone and Pregnancy Rates. Reproduction in Domestic Animals, 47, 131-134
Musilová Darja, Bartoněk Jan, Čech Svatopluk, Páleník Tomáš, Doležel Radovan (2014): Induction of accessory corpus luteum in cows by gonadotropin-releasing hormone administrated after insemination. Acta Veterinaria Brno, 83, 107-111
Peters A.R. (2005): Veterinary clinical application of GnRH—questions of efficacy. Animal Reproduction Science, 88, 155-167
Peters A.R., Martinez T.A., Cook A.J.C. (2000): A meta-analysis of studies of the effect of GnRH 11–14 days after insemination on pregnancy rates in dairy cattle. Theriogenology, 56, 637–647.
Picard-Hagen N., Lhermie G., Florentin S., Merle D., Frein P., Gayrard V. (2015): Effect of gonadorelin, lecirelin, and buserelin on LH surge, ovulation, and progesterone in cattle. Theriogenology, 84, 177-183
Price Christopher A., Carrière Paul D. (2004): Alternate two- and three-follicle wave interovulatory intervals in Holstein heifers monitored for two consecutive estrous cycles. Canadian Journal of Animal Science, 84, 145-147
Robinson RS, Hammond AJ, Wathes DC, Hunter MG, Mann GE (2008): Corpus LuteumEndometriumEmbryo Interactions in the Dairy Cow: Underlying Mechanisms and Clinical Relevance. Reproduction in Domestic Animals, 43, 104-112
Saint-Dizier M, Legendre A-C, Driancourt M-A, Chastant-Maillard S (2014): The Induction of a Secondary Corpus Luteum on Day 12 Post-Ovulation can Delay the Time of Luteolysis in High-Producing Holstein Cows. Reproduction in Domestic Animals, 49, 920-925
Sartori R. (2001): Follicular Deviation and Acquisition of Ovulatory Capacity in Bovine Follicles. Biology of Reproduction, 65, 1403-1409
Souza A.H., Cunha A.P., Silva E.P.B., Gümen A., Ayres H., Guenther J.N., Wiltbank M.C. (2009): Comparison of gonadorelin products in lactating dairy cows: Efficacy based on induction of ovulation of an accessory follicle and circulating luteinizing hormone profiles. Theriogenology, 72, 271-279
Szenci Ottó, Takács Edit, Sulon José, Sousa Noelita Melo de, Beckers Jean-Francois (2006): Evaluation of GnRH treatment 12 days after AI in the reproductive performance of dairy cows. Theriogenology, 66, 1811-1815
Wiltbank Milo, Lopez Hernando, Sartori Roberto, Sangsritavong Siwat, Gümen Ahmet (2006): Changes in reproductive physiology of lactating dairy cows due to elevated steroid metabolism. Theriogenology, 65, 17-29
download PDF

© 2021 Czech Academy of Agricultural Sciences | Prohlášení o přístupnosti