Genetic analysis of the Hungarian population of endangered Hucul horses

Citation:Posta J. (2018): Genetic analysis of the Hungarian population of endangered Hucul horses. Czech J. Anim. Sci., 63: 237-246.
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The population genetic evaluation of the Hungarian Hucul horse population was performed based on pedigree records. Herd book data of registered Hucul horses available up to 2016 were analysed using ENDOG (Gutierrez and Goyache 2005) and POPREP (Groeneveld et al. 2009) on the whole population (WP) as well as on the reference stock (RS) (breeding stock registered in 2016). Inbreeding coefficients were 5.57% (WP) and 7.18% (RS). Average relatedness was 10.39% in WP and higher in RS (12.67%). Effective population size was 52.32. Generation interval was 13.01 years for WP and 10.99 years for RS. The values for equivalent complete generations were 6.07 and 8.75, for the maximum number of generations 14.11 and 19.16, and for the number of full generations traced 3.77 and 5.50 for WP and RS, respectively. The effective number of founders (fe) was 23 both for WP and RS. The effective number of ancestors (fa) was 20 in WP and lower in RS (16). The fa/fe ratio was 0.869 in WP and 0.696 in RS. Founder genome equivalent (fg) was 9.618 in WP and 5.790 in RS. The fg/fe ratio was 0.481 in WP and 0.361 in RS. The study revealed that both the inbreeding coefficient and the average relatedness were high. The above mentioned ratios indicated loss of genetic diversity in the Hungarian Hucul population.

References:
Álvarez I., Royo L.J., Pérez-Pardal L., Fernández I., Payeras L., Goyache F. (2010): Assessing losses of genetic variability in the endangered Mallorquí horse. Czech Journal of Animal Science, 55, 456-462 https://doi.org/10.17221/1700-CJAS
 
Avdi M., Banos G. (2008): Genetic diversity and inbreeding in the Greek Skyros horse. Livestock Science, 114, 362-365 https://doi.org/10.1016/j.livsci.2007.11.007
 
Ballou J.D., Lacy R.C. (1995): Identifying genetically important individuals for management of genetic variation in pedigreed populations. In: Ballou J.D., Gilpin M., Foose T.J. (eds): Population Management for Survival and Recovery: Analytical Methods and Strategies in Small Population Management. Columbia University Press, New York, 76–111.
 
Boichard D, Maignel L, Verrier É (1997): The value of using probabilities of gene origin to measure genetic variability in a population. Genetics Selection Evolution, 29, 5- https://doi.org/10.1186/1297-9686-29-1-5
 
Bokor Á., Jónás D., Ducro B., Nagy I., Bokor J., Szabari M. (2013): Pedigree analysis of the Hungarian Thoroughbred population. Livestock Science, 151, 1-10 https://doi.org/10.1016/j.livsci.2012.10.010
 
CABALLERO ARMANDO, TORO MIGUEL A. (): Interrelations between effective population size and other pedigree tools for the management of conserved populations. Genetical Research, 75, 331-343 https://doi.org/10.1017/S0016672399004449
 
Cervantes I., Goyache F., Molina A., Valera M., Gutiérrez J. P. (2008): Application of individual increase in inbreeding to estimate realized effective sizes from real pedigrees. Journal of Animal Breeding and Genetics, 125, 301-310 https://doi.org/10.1111/j.1439-0388.2008.00755.x
 
Colleau Jean-Jacques (2002): An indirect approach to the extensive calculation of relationship coefficients. Genetics Selection Evolution, 34, 409- https://doi.org/10.1186/1297-9686-34-4-409
 
Curik I. (): Inbreeding, Microsatellite Heterozygosity, and Morphological Traits in Lipizzan Horses. Journal of Heredity, 94, 125-132 https://doi.org/10.1093/jhered/esg029
 
Druml T., Baumung R., Sölkner J. (2009): Pedigree analysis in the Austrian Noriker draught horse: genetic diversity and the impact of breeding for coat colour on population structure. Journal of Animal Breeding and Genetics, 126, 348-356 https://doi.org/10.1111/j.1439-0388.2008.00790.x
 
Dunner Susana, Checa Maria L, Gutierrez Juan P, Martin Juan P, Cañon Javier (1998): Genetic analysis and management in small populations: the Asturcon pony as an example. Genetics Selection Evolution, 30, 397- https://doi.org/10.1186/1297-9686-30-4-397
 
Falconer D.S., Mackay T.F. (1996): Introduction to Quantitative Genetics. Longman Green, Harlow, UK.
 
Frankham R., Ballou J.D., Briscoe D.A. (2002): Introduction to Conservation Genetics. Cambridge University Press, Cambridge, UK.
 
Głażewska Iwona, Jezierski Tadeusz (2004): Pedigree analysis of Polish Arabian horses based on founder contributions. Livestock Production Science, 90, 293-298 https://doi.org/10.1016/j.livprodsci.2004.08.002
 
Groeneveld E., Westhuizen B.V.D., Maiwashe A., Voordewind F., Ferraz J.B.S. (2009): POPREP: a generic report for population management. Genetics and Molecular Research, 8, 1158-1178 https://doi.org/10.4238/vol8-3gmr648
 
Gutierrez J.P., Goyache F. (2005): A note on ENDOG: a computer program for analysing pedigree information. Journal of Animal Breeding and Genetics, 122, 172-176 https://doi.org/10.1111/j.1439-0388.2005.00512.x
 
Gutiérrez J.P., Cervantes I., Goyache F. (2009): Improving the estimation of realized effective population sizes in farm animals. Journal of Animal Breeding and Genetics, 126, 327-332 https://doi.org/10.1111/j.1439-0388.2009.00810.x
 
James J. W. (1962): The spread of genes in random mating control populations. Genetical Research, 3, 1- https://doi.org/10.1017/S0016672300003074
 
James J. W. (1970): The founder effect and response to artificial selection. Genetical Research, 16, 241- https://doi.org/10.1017/S0016672300002500
 
James J.W. (1972): Computation of genetic contributions from pedigrees. Theoretical and Applied Genetics, 42, 272–273.
 
James J. W. (1977): A note on selection differential and generation length when generations overlap. Animal Production, 24, 109-112 https://doi.org/10.1017/S0003356100039271
 
Lacy Robert C. (1989): Analysis of founder representation in pedigrees: Founder equivalents and founder genome equivalents. Zoo Biology, 8, 111-123 https://doi.org/10.1002/zoo.1430080203
 
MacCluer Jean W., VandeBerg John L., Read Bruce, Ryder Oliver A. (1986): Pedigree analysis by computer simulation. Zoo Biology, 5, 147-160 https://doi.org/10.1002/zoo.1430050209
 
Mackowski M., Mucha S., Cholewinski G., Cieslak J. (2015): Genetic diversity in Hucul and Polish primitive horse breeds. Archives Animal Breeding, 58, 23-31 https://doi.org/10.5194/aab-58-23-2015
 
Maignel L., Boichard D., Verrier E. (1996): Genetic variability of French dairy breeds estimated from pedigree information. Interbull Bulletin, 14, 49–54.
 
Martín de la Rosa A.J., Cervantes I., Gutiérrez J.P. (2016): Equivalent effective population size mating as a useful tool in the genetic management of the Ibicenco rabbit breed (Conill Pages d’Eivissa). Czech Journal of Animal Science, 61, 108-116 https://doi.org/10.17221/8783-CJAS
 
Pinheiro M., Kjöllerström H.J., Oom M.M. (2013): Genetic diversity and demographic structure of the endangered Sorraia horse breed assessed through pedigree analysis. Livestock Science, 152, 1-10 https://doi.org/10.1016/j.livsci.2012.11.017
 
Pjontek J., Kadlečík O., Kasarda R., Horný M. (2012): Pedigree analysis in four Slovak endangered horse breeds. Czech Journal of Animal Science, 57, 54-64 https://doi.org/10.17221/5132-CJAS
 
Royo L.J., Álvarez I., Gutiérrez J.P., Fernández I., Goyache F. (2007): Genetic variability in the endangered Asturcón pony assessed using genealogical and molecular information. Livestock Science, 107, 162-169 https://doi.org/10.1016/j.livsci.2006.09.010
 
Sevinga M., Vrijenhoek T., Hesselink J. W., Barkema H. W., Groen A. F. (2004): Effect of inbreeding on the incidence of retained placenta in Friesian horses1. Journal of Animal Science, 82, 982-986 https://doi.org/10.2527/2004.824982x
 
Sölkner J., Filipcic L., Hampshire N. (1998): Genetic variability of populations and similarity of subpopulations in Austrian cattle breeds determined by analysis of pedigrees. Animal Science, 67, 249-256 https://doi.org/10.1017/S1357729800010006
 
Valera M., Molina A., Gutiérrez J.P., Gómez J., Goyache F. (2005): Pedigree analysis in the Andalusian horse: population structure, genetic variability and influence of the Carthusian strain. Livestock Production Science, 95, 57-66 https://doi.org/10.1016/j.livprodsci.2004.12.004
 
Vigh Zs., Csato L., Nagy I. (2008): Application of pedigree analysis in the animal breeding programs. (Hungarian Journal of) Animal Production, 57, 549–564. (in Hungarian)
 
Vostrá-Vydrová H., Vostrý L., Hofmanová B., Krupa E., Zavadilová L. (2016): Pedigree analysis of the endangered Old Kladruber horse population. Livestock Science, 185, 17-23 https://doi.org/10.1016/j.livsci.2016.01.001
 
Vostrý L., Čapková Z., Přibyl J., Hofmanová B., Vostrá Vydrová H., Mach K (2011): Population structure of Czech cold-blooded breeds of horses. Archives Animal Breeding, 54, 1-9 https://doi.org/10.5194/aab-54-1-2011
 
Wright S. (1922): Coefficients of inbreeding and relationhip. American Neptune, 56, 330–333.
 
Wright S. (1931): Evolution in Mendelian populations. Genetics, 16, 97–159.
 
Zechner P, Sölkner J, Bodo I, Druml T, Baumung R, Achmann R, Marti E, Habe F, Brem G (2002): Analysis of diversity and population structure in the Lipizzan horse breed based on pedigree information. Livestock Production Science, 77, 137-146 https://doi.org/10.1016/S0301-6226(02)00079-9
 
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