Associations of fifty single nucleotide polymorphisms within candidate genes with meatness in pigs
A. Borowska, T. Szwaczkowski, M. Koćwin-Podsiadła, S. Kamiński, A. Ruść, E. Krzęcio-Nieczyporukhttps://doi.org/10.17221/7403-CJASCitation:Borowska A., Szwaczkowski T., Koćwin-Podsiadła M., Kamiński S., Ruść A., Krzęcio-Nieczyporuk E. (2014): Associations of fifty single nucleotide polymorphisms within candidate genes with meatness in pigs. Czech J. Anim. Sci., 59: 227-237.
The objective of the paper was to classify 50 SNPs (from 17 chromosomes) according to their contribution to the meatness of 293 boars of two breeds (Polish Landrace and Polish Large White) using entropy analysis and standard association analysis. The collected data were classified into two groups (according to the official EUROP procedure) and used for entropy analysis. Associations of single genotypes versus their groups (located at single chromosomes) with the trait studied were estimated by the use of the Generalized Linear Model (GLM). Thus meatness was included as a continuous variable. The most important contributions have been estimated by both approaches for the following SNPs: SULT1A1:g.76G>A (SSC3), PKLR:g.384C>T (SSC4), MYOD1:c.566G>C (SSC2), TNNT3:g.153T>C (SSC2), GAA:g.38T>C (SSC12), LDLRR1:c.459A>G (SSC8), MYF6:g.255T>C (SSC5), CAS:g.499A>C (SSC2), PPARGC:c.678T>A (SSC15). Moreover, interactions among some studied loci are suggested, especially for the loci at chromosome 1.Keywords:
entropy analysis; pork; meat content; SNP