Serotonin, GnRH-A, and dopamine interaction in the control of in vivo luteinizing hormone release in Prussian carp (Carassius gibelio Bloch) at the time of gonad recrudescence M., Gajdzinski D., Gosiewski G., Socha M. (2015): Serotonin, GnRH-A, and dopamine interaction in the control of in vivo luteinizing hormone release in Prussian carp (Carassius gibelio Bloch) at the time of gonad recrudescence. Czech J. Anim. Sci., 60: 45-51.
download PDF
The effects of serotonin (5-HT), GnRH analogue (D-Ala6 LHRH, GnRH-A) and dopamine antagonist – pimozide (PIM), on luteinizing hormone (LH) release in mature Prussian carp female (Carassius gibelio Bloch) were examined at the time of gonad recrudescence. Fish were intraperitoneally injected with 5-HT (10 mg/kg), GnRH-A (20 μg/kg) or PIM (5 mg/kg) or the combinations: 5-HT+GnRH-A, 5-HT+PIM, 5-HT+GnRH-A+PIM. Before the injection and 3, 6, 12 or 24 h after treatment blood samples were collected for LH levels determination by ELISA method. The analysis of LH concentrations, expressed as the percentage of pre-treatment, showed that serotonin alone had no influence on the spontaneous LH release, however the additive effects of serotonin and GnRH-A was observed. Serotonin potentiated the GnRH-A-stimulated LH release and potentiated also the effect of PIM. Extremely strong response to PIM and also to the combination with GnRH-A masked the participation of serotonin in the process of LH release in fish with recrudescing gonads. The interaction of serotonin GnRH-A and PIM in the control of LH release is discussed.
Batten T.F.C., Berry P.A., Maqbool A., Moons L., Vandesande F. (1993): Immunolocalization of catecholamine enzymes, serotonin, dopamine and L-dopa in the brain o/.f dicentrarchus labrax (teleostei). Brain Research Bulletin, 31, 233-252
Brooks Bryan W., Foran Christy M., Richards Sean M., Weston James, Turner Philip K., Stanley Jacob K., Solomon Keith R., Slattery Marc, La Point Thomas W. (2003): Aquatic ecotoxicology of fluoxetine. Toxicology Letters, 142, 169-183
Brooks B.W., Chambliss C.K., Stanley J.K., Ramirez A., Banks K.E., Johnson R.D., Lewis R.J. (2005): Determination of select antidepressants in fish from an effluent-dominated stream. Environmental Toxicology and Chemistry, 24, 464–469.
Chemineau P., Daveau A., Pelletier J., Malpaux B., Karsch F.J., Viguie C. (2003): Changes in the 5-HT2A receptor system in the pre-mammillary hypothalamus of the ewe are related to regulation of LH pulsatile secretion by an endogenous circannual rhythm. BMC Neuroscience, 4, 1–14.
Corio M., Peute J., Steinbusch H.W.M. (1991): Distribution of serotonin- and dopamine-immunoreactivity in the brain of the teleost Clarias gariepinus. Journal of Chemical Neuroanatomy, 4, 79-95
Dow R.C., Williams B.C., Bennie J., Carroll S., Fink G. (1994): A central 5-HT2 receptor mechanism plays a key role in the proestrous surge of luteinizing hormone in the rat. Psychoneuroendocrinology, 19, 395-399
Dulka J.G., Sloley B.D., Stacey N.E., Peter R.E. (1992): A reduction in pituitary dopamine turnover is associated with sex pheromone-induced gonadotropin secretion in male goldfish. General and Comparative Endocrinology, 86, 496–505.
Ekstr�m Peter, Van Veen Theo (1984): Distribution of 5-hydroxytryptamine (serotonin) in the brain of the teleostGasterosteus aculeatus L.. The Journal of Comparative Neurology, 226, 307-320
Frankenhuis-van den Heuvel T. H. M., Nieuwenhuys R. (1984): Distribution of serotonin-immunoreactivity in the diencephalon and mesencephalon of the trout, Salmo gairdneri. Anatomy and Embryology, 169, 193-204
Groves DavidJ., Batten TrevorF.C. (1985): Ultrastructural autoradiographic localization of serotonin in the pituitary of a teleost fish, Poecilia latipinna. Cell and Tissue Research, 240, -
Kah O., Chambolle P. (1983): Serotonin in the brain of goldfish Carassius auratus: an immunohistochemical study. Cell and Tissue Research, 234, 319–333.
Kah Olivier, Dulka Joseph G., Dubourg Pierrette, Thibaulf Jean, Peter Richard E. (1987): Neuroanatomical Substrate for the Inhibition of Gonadotrophin Secretion in Goldfish: Existence of a Dopaminergic Preoptico-Hypophyseal Pathway. Neuroendocrinology, 45, 451-458
Kah O. (1989): Development of an enzyme-linked immunosorbent assay for goldfish gonadotropin. Biology of Reproduction, 41, 68-73
Khan Izhar A., Thomas Peter (1992): Stimulatory effects of serotonin on maturational gonadotropin release in the Atlantic croaker, Micropogonias undulatus. General and Comparative Endocrinology, 88, 388-396
Khan Izhar A., Thomas Peter (1993): Immunocytochemical Localization of Serotonin and Gonadotropin-Releasing Hormone in the Brain and Pituitary Gland of the Atlantic Croaker Micropogonias undulatus. General and Comparative Endocrinology, 91, 167-180
Khan Izhar A., Thomas Peter (1994): Seasonal and daily variations in the plasma gonadotropin II response to a LHRH analog and serotonin in Atlantic croaker (Micropogonias undulatus): Evidence for mediation by 5-HT2 receptors. Journal of Experimental Zoology, 269, 531-537
Kolpin Dana W., Furlong Edward T., Meyer Michael T., Thurman E. Michael, Zaugg Steven D., Barber Larry B., Buxton Herbert T. (2002): Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000:  A National Reconnaissance. Environmental Science & Technology, 36, 1202-1211
Le Corre S., Chemineau P. (1993a): Control of photoperiodic inhibition of luteinizing hormone secretion by dopaminergic and serotonergic systems in ovariectomized Ile-de-France ewes supplemented with oestradiol. Journal of Reproduction and Fertility, 97, 367–373.
Le Corre S., Chemineau P. (1993b): Serotonergic 5HT2-receptors mediate the inhibitory action of serotonin on LH secretion in ovariectomized, estradiol-treated ewes that are refractory to short days. Biology of Reproduction, 49, 140–147.
Lethimonier Christèle, Madigou Thierry, Muñoz-Cueto José-Antonio, Lareyre Jean-Jacques, Kah Olivier (2004): Evolutionary aspects of GnRHs, GnRH neuronal systems and GnRH receptors in teleost fish. General and Comparative Endocrinology, 135, 1-16
Levavi-Sivan B., Bogerd J., Mañanós E.L., Gómez A., Lareyre J.J. (2010): Perspectives on fish gonadotropins and their receptors. General and Comparative Endocrinology, 165, 412-437
Margolis-Kazan H., Halpern-Sebold L., Schreibman M. (1985): Immunocytochemical localization of serotonin in the brain and pituitary gland of platyfish Xiphophorus maculatus. Cell and Tissue Research, 240, 311–314.
Mennigen Jan A., Harris Ed A., Chang John P., Moon Thomas W., Trudeau Vance L. (2009): Fluoxetine affects weight gain and expression of feeding peptides in the female goldfish brain. Regulatory Peptides, 155, 99-104
Mennigen J.A., Stroud P., Zamora J.M., Moon T.W., Trudeau V.L. (2011): Pharmaceuticals as neuroendocrine disruptors: lesson learned from fish on Prozac. Journal of Toxicology and Environmental Health, 14, 387–412.
Metcalfe Chris D., Chu Shaogang, Judt Colin, Li Hongxia, Oakes Ken D., Servos Mark R., Andrews David M. (2010): Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed. Environmental Toxicology and Chemistry, 29, 79-89
Mikolajczyk Tomasz, Chyb Jaroslaw, Szczerbik Pawel, Sokolowska-Mikolajczyk Miroslawa, Epler Piotr, Enright William J, Filipiak Maria, Breton Bernard (2004): Evaluation of the potency of azagly-nafarelin (GnRH analogue), administered in combination with different formulations of pimozide, on LH secretion, ovulation and egg quality in common carp (Cyprinus carpio L.) under laboratory, commercial hatchery and natural conditions. Aquaculture, 234, 447-460
Peter R.E., Yu K.L. (1997): Neuroendocrine regulation of ovulation in fishes: basic and applied aspects. Reviews in Fish Biology and Fisheries, 7, 173–197.
Pinilla L., Ranchal A., Aguilar R., Aguilar E. (1994): Role of the serotoninergic system in the control of gonadotropin secretion in prepubertal male rats. European Journal of Endocrinology, 130, 617–624.
Rodriguez M., Feleder C., Szwarcfarb B., Scacchi P., Arias P., Moguilevsky J. (1994): Mediobasal hypothalamic perifusion with serotonin inhibits steroid-stimulated LH secretion: assessment with push-pull technique. Neuroendocrinology Letters, 16, 121–129.
Saligaut Christian, Salbert Gilles, Bailhache Thierry, Bennani Sanae, Jego Patrick (1992): Serotonin and dopamine turnover in the female rainbow trout (Oncorhynchus mykiss) brain and pituitary: Changes during the annual reproductive cycle. General and Comparative Endocrinology, 85, 261-268
Schulz R.W., Goos H.J. (1999): Puberty in male fish: concepts and recent developments with special reference to African catfish (Clarias gariepinus). Aquaculture, 177, 5–12.
Semsar Katharine, Perreault Heidi A.N., Godwin John (2004): Fluoxetine-treated male wrasses exhibit low AVT expression. Brain Research, 1029, 141-147
Senthilkumaran B., Joy K.P. (1993): Annual Variations in Hypothalamic Serotonin and Monoamine Oxidase in the Catfish Heteropneustes fossilis with a Note on Brain Regional Differences of Day-Night Variations in Gonadal Preparatory Phase. General and Comparative Endocrinology, 90, 372-382
Senthilkumaran B., Okuzawa K., Gen K., Kagawa H. (2001): Effects of Serotonin, GABA and Neuropeptide Y on Seabream Gonadotropin Releasing Hormone Release In Vitro from Preoptic-Anterior Hypothalamus and Pituitary of Red Seabream, Pagrus major. Journal of Neuroendocrinology, 13, 395-400
Sokolowska M., Peter R.E., Nahorniak C.S., Chang J.P. (1985): Seasonal effects of pimozide and des-Gly10 (D-Ala6) LHRH ethylamide on gonadotropin secretion in goldfish. General and Comparative Endocrinology, 57, 472–479.
Sokolowska-Mikolajczyk M., Socha M., Mikolajczyk T., Chyb J., Epler P. (2002): Seasonal short-term effects of naltrexone on LH secretion in male carp (Cyprinus carpio L.). Comparative Biochemistry and Physiology, Part C, 131, 379–385.
Somoza Gustavo M., Peter Richard E. (1991): Effects of serotonin on gonadotropin and growth hormone release from in vitro perifused goldfish pituitary fragments. General and Comparative Endocrinology, 82, 103-110
Somoza Gustavo M., Yu Kei L., Peter Richard E. (1988): Serotonin stimulates gonadotropin release in female and male goldfish, Carassius auratus L. General and Comparative Endocrinology, 72, 374-382
Subhedar N., Cerda J., Calman B.G., Wallace R.A. (1997): Changes in forebrain and pituitary dopamine and serotonin contents of female Fundulus during its biweekly reproductive cycle. Comparative Biochemistry and Physiology, 118A, 577–584.
Trudeau V.L., Sloley B.D., Wong A.O.L., Peter R.E. (1993): Interactions of Gonadal Steroids with Brain Dopamine and Gonadotropin-Releasing Hormone in the Control of Gonadotropin-II Secretion in the Goldfish. General and Comparative Endocrinology, 89, 39-50
Wong A.O.L., Murphy C.K., Chang J.P., Neumann C.M., Lo A., Peter R.E. (1998): Direct actions of serotonin on gonadotropin-II and growth hormone release from goldfish pituitary cells: interactions with gonadotropin releasing hormone and dopamine and further evaluation of serotonin receptor specificity. Fish Physiology and Biochemistry, 19, 23–34.
Yu K.L., Rosenblum P.M., Peter R.E. (1991): In vitro release of gonadotropin-releasing hormone from the brain preoptic-anterior hypothalamic region and pituitary of female goldfish. General and Comparative Endocrinology, 81, 256–267.
Zohar J., Munoz-Cueto J.A., Elizur A., Kah O. (2010): Neuroendocrinology of reproduction in teleost fish. General and Comparative Endocrinology, 165, 438–455.
download PDF

© 2022 Czech Academy of Agricultural Sciences | Prohlášení o přístupnosti