Sclerosing sialadenitis of the sublingual salivary glands in a cat V., Cecen Ayalp G., Akgul M.B., Akbala M., Sonmez G. (2018): Sclerosing sialadenitis of the sublingual salivary glands in a cat. Veterinarni Medicina, 63: 575-578.
download PDF

In this report, sclerosing sialadenitis of the sublingual salivary glands is described in a three-year-old, male, mixed breed cat. Sublingual masses were dissected and removed under dissociative anaesthesia. The patient had recovered completely at two months post-surgery. The two soft and pale red masses were 1.5 × 1 × 0.5 cm in size. Histologically, it was observed that the masses were covered with stratified squamous epithelium containing large numbers of salivary glands and ducts in the collagen-rich loose connective tissue. Scattered lymphocyte infiltrations were observed in the connective tissue. Mild to severe lymphocyte infiltration was seen between salivary glands. Some glands exhibited severe fibrosis, epithelial destruction and atrophy. To the best of our knowledge, this is the first report of sclerosing sialadenitis in a cat. Chronic sclerosing sialadenitis (Kuttner’s tumour) is a condition that has been defined in humans. Histological findings similar to those of Kuttner’s tumour were observed in this case, and dense plasma cell infiltrations suggested immune-mediated plasmacytic disease, which has been reported as a potential aetiology of Kuttner’s tumour. Corticosteroid therapy was not attempted, and the patient was treated successfully using surgical excision.

Abe Takahiro, Sato Tsuyoshi, Tomaru Yasuhisa, Sakata Yasuaki, Kokabu Shoichiro, Hori Naoko, Kobayashi Akio, Yoda Tetsuya (2009): Immunoglobulin G4–related sclerosing sialadenitis: report of two cases and review of the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 108, 544-550
Boydell P., Pike R., Crossley D. (2000): Presumptive sialadenosis in a cat. Journal of Small Animal Practice, 41, 573-574
Brooks DG, Hottinger HA, Dunstan RW (1995): Canine necrotizing sialometaplasia: a case report and review of the literature. Journal of the American Animal Hospital Association, 31, 21-25
Brown P.J., Bradshaw J.M., Sozmen M., Campbell R.H. (2016): Feline necrotising sialometaplasia: A report of two cases. Journal of Feline Medicine and Surgery, 6, 279-281
Chan John K. C. (1998): Kuttner Tumor (Chronic Sclerosing Sialadenitis) of the Submandibular Gland. Advances in Anatomic Pathology, 5, 239-251
Hammer A, Getzy D, Ogilvie G, Upton M, Klausner J, Kisseberth WC (2001): Salivary gland neoplasia in the dog and cat: survival times and prognostic factors. Journal of the American Animal Hospital Association, 37, 478-482
HARRISON J.D., EPIVATIANOS A., BHATIA S.N. (1997): Role of microliths in the aetiology of chronic submandibular sialadenitis: a clinicopathological investigation of 154 cases. Histopathology, 31, 237-251
Kitagawa Satoshi, Zen Yoh, Harada Kenichi, Sasaki Motoko, Sato Yasunori, Minato Hiroshi, Watanabe Kishichiro, Kurumaya Hiroshi, Katayanagi Kazuyoshi, Masuda Shinji, Niwa Hideki, Tsuneyama Koichi, Saito Katsuhiko, Haratake Joji, Takagawa Kiyoshi, Nakanuma Yasuni (2005): Abundant IgG4-Positive Plasma Cell Infiltration Characterizes Chronic Sclerosing Sialadenitis (K??ttner??s Tumor). The American Journal of Surgical Pathology, 29, 783-791
Kuttner H (1896): About inflammatory tumours of the submaxillar salivary gland (in German). Bruns’ Beitrage Zur Klinischen Chirurgie 15, 815–828.
Langley-Hobbs S (2014): The head and neck. In: Langley-Hoobs SJ, Demetriou JL, Ladlow JF (eds): Feline Soft Tissue and General Surgery. Saunders. 571–586.
Mawby DI, Bauer MS, Lloyd-Bauer PM, Clark EG (1991): Vasculitis and necrosis of the mandibular salivary glands and chronic vomiting in a dog. The Canadian Veterinary Journal 32, 562–564.
Pandarakalam Cyril, Goebel William M., Seyer Bradley (2013): Chronic sclerosing sialadenitis or Küttner's tumor associated with a giant sialolith: a case report. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 115, e38-e40
Novaes Pinheiro T. (2010): Chronic Sclerosing Sialadenitis (Kuttner Tumor) in the sublingual gland: unusual manifestation related to partial edentulism and chronic masticatory trauma.. Journal of Clinical and Experimental Dentistry, , e177-e179
Seifert G (1992): Tumour-like lesions of the salivary glands. The new WHO classification. Pathology, Research and Practice 188, 836–846.
Seifert G, Donath K (1977): On the pathogenesis of the Kuttner tumor of the submandibular gland – analysis of 349 cases with chronic sialadenitis of the submandibular. HNO 25, 81–92.
Tiemann Markus, Teymoortash Afshin, Schrader Carsten, Werner Jochen A., Parwaresch Reza, Seifert Gerhard, Klöppel Günter (2002): Chronic Sclerosing Sialadenitis of the Submandibular Gland is Mainly Due to a T Lymphocyte Immune Reaction. Modern Pathology, 15, 845-852
download PDF

© 2018 Czech Academy of Agricultural Sciences