Monitoring the avermectin and pyrantel resistance status of nematode parasites of horses in the Czech Republic S., Svetlikova J., Hargitaiova K., Kecerova Z., Mrackova M. (2018): Monitoring the avermectin and pyrantel resistance status of nematode parasites of horses in the Czech Republic. Veterinarni Medicina, 63: 299-305.
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The avermectin and pyrantel resistance of equine parasites was monitored on four farms in the Czech Republic in 2014. The aim of the testing was to investigate the anthelmintic resistance of cyathostomins and ascarids. One hundred and eighty-six horses were included in the test, 54 of which were infected by ascarids and 174 by cyathostomins. Faecal egg count reduction tests were used to assess anthelmintic resistance. The faecal egg count reduction for ascarids was within the range of 87.9% to 100% for avermectins and 100% for pyrantel embonate. Faecal egg count reduction for cyathostomins ranged from 99% to 100% for avermectins and 89.3% to 98.2% for pyrantel embonate.

Austin SM, DiPietro JA, Foreman JH, Baker GJ, Todd KS (1991): Comparison of the efficacy of ivermectin, oxibendazole, and pyrantel pamoate against 28-day Parascaris equorum larvae in the intestine of pony foals. Journal of the American Veterinary Medical Association 198, 1946–1949.
Bodeček Štěpán, Vavrouchová Eva (2013): Monitoring of anthelmintic resistance in small strongyles in the Czech Republic in the years 2006–2009. Acta Veterinaria Brno, 82, 243-248
Boersema J. H., Eysker M., Nas J. W. M. (2002): Apparent resistance of Parascaris equorum to macrocylic lactones. Veterinary Record, 150, 279-281
Brady Heidi A., Nichols Wade T. (2009): Drug Resistance in Equine Parasites: An Emerging Global Problem. Journal of Equine Veterinary Science, 29, 285-295
Canever Ricardo J., Braga Pollyana R.C., Boeckh Albert, Grycajuck Marcelly, Bier Daniele, Molento Marcelo B. (2013): Lack of Cyathostomin sp. reduction after anthelmintic treatment in horses in Brazil. Veterinary Parasitology, 194, 35-39
Chroust K (1998): The first occurrence of anthelmintic resistance in strongylid nematodes of sheep and horses in Czech Republic. Parasitology International, 47, 242-
Coles G.C., Bauer C., Borgsteede F.H.M., Geerts S., Klei T.R., Taylor M.A., Waller P.J. (1992): World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Veterinary Parasitology, 44, 35-44
Craig T.M., Diamond P.L., Ferwerda N.S., Thompson J.A. (2007): Evidence of Ivermectin Resistance by Parascaris equorum on a Texas Horse Farm. Journal of Equine Veterinary Science, 27, 67-71
CRAVEN J., BJØRN H., HENRIKSEN S. A., NANSEN P., LARSEN M., LENDAL S. (1998): Survey of anthelmintic resistance on Danish horse farms, using 5 different methods of calculating faecal egg count reduction. Equine Veterinary Journal, 30, 289-293
Hearn F. Patrick D., Peregrine Andrew S. (2003): Identification of foals infected with Parascaris equorum apparently resistant to ivermectin. Journal of the American Veterinary Medical Association, 223, 482-485
Herd R. P. (1990): Equine parasite control - Problems associated with intensive anthelmintic therapy. Equine Veterinary Education, 2, 41-47
Ihler CF (1995): A field survey on anthelmintic resistance in equine small strongyles in Norway. Acta Veterinaria Scandinavica 36, 135–143.
Kaplan Ray M. (2002): Anthelmintic resistance in nematodes of horses. Veterinary Research, 33, 491-507
Kaplan Ray M. (2004): Drug resistance in nematodes of veterinary importance: a status report. Trends in Parasitology, 20, 477-481
Kaplan R. M., Nielsen M. K. (2010): An evidence-based approach to equine parasite control: It ain't the 60s anymore. Equine Veterinary Education, 22, 306-316
Kaplan Ray M., Klei Thomas R., Lyons Eugene T., Lester Guy, Courtney Charles H., French Dennis D., Tolliver Sharon C., Vidyashankar Anand N., Zhao Ying (2004): Prevalence of anthelmintic resistant cyathostomes on horse farms. Journal of the American Veterinary Medical Association, 225, 903-910
Langrova I (1998): Seasonal prevalence and intensity of faecal helminth egg (larval) output in various categories of herds of horses during two grazing seasons. Helminthologia 35, 43–50.
Lyons E. T., Drudge J. H., Tolliver S. C. (1976): Studies on the Development and Chemotherapy of Larvae of Parascaris equorum (Nematoda: Ascaridoidea) in Experimentally and Naturally Infected Foals. The Journal of Parasitology, 62, 453-
Lyons E.T., Drudge J.H., Tolliver Sharon C. (2000): Larval Cyathostomiasis. Veterinary Clinics of North America: Equine Practice, 16, 501-513
Lyons E. T., Tolliver S. C., Ionita M., Collins S. S. (2008): Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007. Parasitology Research, 103, 287-291
Lyons E. T., Tolliver S. C., Ionita M., Lewellen A., Collins S. S. (2008): Field studies indicating reduced activity of ivermectin on small strongyles in horses on a farm in Central Kentucky. Parasitology Research, 103, 209-215
Näreaho A., Vainio K., Oksanen A. (2011): Impaired efficacy of ivermectin against Parascaris equorum, and both ivermectin and pyrantel against strongyle infections in trotter foals in Finland. Veterinary Parasitology, 182, 372-377
Nielsen MK, Wang J, Davis R, Bellaw JL, Lyons ET, Lear TL, Goday C (2014): Parascaris univalens – a victim of large-scale misidentification? Parasitology Research 113, 4485–4490.
Lind Eva, Christensson Dan (2009): Anthelmintic efficacy on Parascaris equorum in foals on Swedish studs. Acta Veterinaria Scandinavica, 51, 45-
Lind E. Osterman, Kuzmina T., Uggla A., Waller P. J., Höglund J. (2007): A Field Study on the Effect of Some Anthelmintics on Cyathostomins of Horses in Sweden. Veterinary Research Communications, 31, 53-65
Porr Cheryl A. Shea, Hedinger Victoria F., Hamm Lauren R., Ernst Morgan M., Papajeski Barbie M., Santiago Michelle L., Davis Amanda J. (2017): Effects of Ivermectin and Moxidectin on Fecal Egg Count and Egg Reappearance Rate in Horses. Journal of Equine Veterinary Science, 57, 51-55
Prichard R. K., Hall C. A., Kelly J. D., Martin I. C. A., Donald A. D. (1980): THE PROBLEM OF ANTHELMINTIC RESISTANCE IN NEMATODES. Australian Veterinary Journal, 56, 239-250
Reinemeyer Craig R (2009): Diagnosis and control of anthelmintic-resistant Parascaris equorum. Parasites & Vectors, 2, S8-
Reinemeyer Craig R. (2012): Anthelmintic resistance in non-strongylid parasites of horses. Veterinary Parasitology, 185, 9-15
Reinemeyer CR, Prado JC, Vaala W (2010): Larvicidal efficacy of fenbendazole against a macrocyclic lactone-resistant isolate of Parascaris equorum. Proceedings of the American Association of Veterinary Parasitologists 55, 49.
Relf Valerie E., Lester Hannah E., Morgan Eric R., Hodgkinson Jane E., Matthews Jacqueline B. (2014): Anthelmintic efficacy on UK Thoroughbred stud farms. International Journal for Parasitology, 44, 507-514
Sangster NC (1999): Pharmacology of anthelmintic resistance in cyathostomes: will it occur with the avermectins/milbemycins? Veterinary Parasitology 85, 189–204.
Schougaard H., Nielsen M. K. (2007): Apparent ivermectin resistance of Parascaris equorum in foals in Denmark. Veterinary Record, 160, 439-440
Slocombe J. Owen D., de Gannes Rolph V.G., Lake Mary C. (2007): Macrocyclic lactone-resistant Parascaris equorum on stud farms in Canada and effectiveness of fenbendazole and pyrantel pamoate. Veterinary Parasitology, 145, 371-376
Smith M.A., Nolan T.J., Rieger R., Aceto H., Levine D.G., Nolen-Walston R., Smith B.I. (2015): Efficacy of major anthelmintics for reduction of fecal shedding of strongyle-type eggs in horses in the Mid-Atlantic region of the United States. Veterinary Parasitology, 214, 139-143
Traversa D, Parente FI, Iorio R, Gatti A, Bartolini R, Fusco M, Di Lucente A, Paoletti B, Costanzo F, Klei T (2007): Valutazione dell efficacia dell oxibendazolo e della moxidectina neiconfronti dei cyathostomini resistenci al fenbendazolo. XIII Congresso Multisala SIVE, Italy Bologna 2007. 193–194.
Traversa Donato, Castagna Giuseppe, von Samson-Himmelstjerna Georg, Meloni Silvana, Bartolini Roberto, Geurden Thomas, Pearce Michael C., Woringer Emmanuel, Besognet Bruno, Milillo Piermarino, D’Espois Melanie (2012): Efficacy of major anthelmintics against horse cyathostomins in France. Veterinary Parasitology, 188, 294-300
Várady M, Königová A, Čorba J (2000): Benzimidazole resistance in equine cyathostomes in Slovakia. Veterinary Parasitology, 94, 67-74
Veronesi F, Fioretti DP, Genchi C (2010): Are macrocyclic lactones useful drugs for the treatment of Parascaris equorum infections in foals? Veterinary Parasitology 172, 164–167.
von Samson-Himmelstjerna G., Fritzen B., Demeler J., Schürmann S., Rohn K., Schnieder T., Epe C. (2007): Cases of reduced cyathostomin egg-reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms. Veterinary Parasitology, 144, 74-80
Wirtherle N., Schnieder T., von Samson-Himmelstjerna G. (2004): Prevalence of benzimidazole resistance on horse farms in Germany. Veterinary Record, 154, 39-41
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