Clinical application of both amniotic membranes and adipose derived mesenchymal stem cells in a cat with a large skin defect

https://doi.org/10.17221/155/2020-VETMEDCitation:

Kim J, Kim D, Seo D, Hwang H, Kim Y, Chung T, Lim S, Lee H, Kim M, Park S, Youn H (2022): Clinical application of both amniotic membranes and adipose derived mesenchymal stem cells in a cat with a large skin defect. Vet Med-Czech 67, 105–111.

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Surgical procedures on large skin defects can be challenging in the short term due to the size of the lesion, infection, and tissue defect. A regenerative therapy for skin wounds has been applied to promote the healing process. An 8-month-old, Korean domestic short-haired female cat, weighing 3 kg, was rescued with extensive defects on the right flank to right inguinal region caused by bite wounds. In this case, amniotic membranes and adipose-derived mesenchymal stem cells were used as the regenerative therapy to treat the large skin defect rather than a surgical intervention alone. To the best of our knowledge, this is the first report of a case with of a large skin defect treated by applying allogeneic amniotic membranes and allogeneic mesenchymal stem cells to a cat.

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