Effect of a GnRH agonist (deslorelin) on ovarian activity in leopard geckos (Eublepharis macularius)

https://doi.org/10.17221/167/2018-VETMEDCitation:Cermakova E., Oliveri M., Knotkova Z., Knotek Z. (2019): Effect of a GnRH agonist (deslorelin) on ovarian activity in leopard geckos (Eublepharis macularius). Veterinarni Medicina, 64: 228-230.
download PDF

The aim of this study was to evaluate the effectiveness of deslorelin acetate in the regulation of reproductive activity in captive leopard geckos (Eublepharis macularius). Fourteen healthy adult females were separated into two groups. Under general anaesthesia, deslorelin acetate implants (4.7 mg) or placebo implants were administered into the coelom of ten female geckos and four female geckos, respectively. One healthy adult male Leopard gecko was added to each group of females (five females with GnRH implants and two females with placebo implants). The geckos were regularly monitored over two breeding seasons (visual examination, weight control). Nesting sites were checked daily. There were no postoperative complications or any other health problems during the study. Implant administration did not result in long-term suppression of reproductive function. No significant differences were found in the number of clutches between the female groups (deslorelin implants versus placebo implants) or in the number of clutches between the two breeding seasons. Deslorelin acetate implants did not interfere with ovarian activity in captive female leopard geckos. The use of GnRH agonist implants is not an appropriate method for control of reproductive function in female leopard geckos.

References:
Dorrestein GM, Noule S, Kik MJL, Knotkova Z, Dieleman SJ, Knotek Z (2007): Steroid hormone concentration related to preovulatory follicle stasis in the green iguana (I. iguana). Proceedings of the 43rd International Symposium on Diseases of Zoo and Wild Animals, 96–101.
 
Kirchgessner Megan, Mitchell Mark, Domenzain Luis, Walden Michael, Dickens Molly J., Romero L. Michael (2009): Evaluating the Effect of Leuprolide Acetate on Testosterone Levels in Captive Male Green Iguanas (Iguana iguana). Journal of Herpetological Medicine and Surgery, 19, 128-131  https://doi.org/10.5818/1529-9651-19.4.128
 
Kneidinger N (2009): GnRH implant in green iguana (Iguana iguana). [Diploma Thesis] University of Veterinary Medicine Vienna, 29 pp.
 
Knotek Z, Knotkova Z, Kley N, Moestl E, Kneidinger N (2009): Is ovariectomy in female lizards necessary? Clinical study with GnRH analogue implants in Green Iguanas. Proceedings of BVZS Autumn Meeting London, 76.
 
Knotek Z (2013): Hormonal contraception for reptiles. Proceedings of the 31st World Veterinary Congress Prague, 10–14 p.
 
Knotek Z (2014): Reproductive strategies in captive female veiled chameleons. Proceedings of the UPAV/AAVAC/ARAV Conference, Cairns, 127–130 p.
 
Knotek Z, Cermakova E, Oliveri M (2017): Reproductive medicine in lizards. Veterinary Clinics of North America: Exotic Animal Practice 20, 411–438.
 
Knotek Z. (2017): Induction to inhalation anaesthesia in agamid lizards with alfaxalone. Veterinární Medicína, 62, 41-43  https://doi.org/10.17221/91/2016-VETMED
 
Kummrow Maya S., Smith Dale A., Crawshaw Graham, Mastromonaco Gabriela F. (2010): Characterization of fecal hormone patterns associated with the reproductive cycle in female veiled chameleons (Chamaeleo calyptratus). General and Comparative Endocrinology, 168, 340-348  https://doi.org/10.1016/j.ygcen.2010.04.022
 
download PDF

© 2019 Czech Academy of Agricultural Sciences