The effect of brown seaweed and polyphenol supplementation in male rabbits on the blood profile and antioxidant markers

https://doi.org/10.17221/26/2022-VETMEDCitation:

Knizatova N, Massanyi M, Rossi R, Ondruska L, Kovacik A, Tokarova K, Gren A, Formicki G, Binkowski L, Halo M, Lukac N, Massanyi P, Vizzarri F (2022): The effect of brown seaweed and polyphenol supplementation in male rabbits on the blood profile and antioxidant markers. Vet Med-Czech 67, 527–537.

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Currently, in animal nutrition, the replacement of synthetic substances with natural ones was expected to improve animal health. The aim of the present study was to evaluate the effects of a dietary brown seaweed and plant polyphenol mixture in adult male rabbits on the haematological profile and antioxidant markers. Twenty-four adult male rabbits were divided into three experimental groups receiving a control diet (C) or diets supplemented with 0.3% (T1) and 0.6% (T2) of a feed additive containing brown seaweed (Laminaria spp.) and plant extracts of seaweed origin. The trial lasted for 90 days. A lower potassium concentration was observed at 30 days in the T2 group, compared with the T1 and C groups. An increase in the antioxidant status was observed (P < 0.05) from day 60 of the trial in the rabbits fed diets with an algae-polyphenolic supplement (T1 and T2 groups). Concluding, the diet supplementation of brown seaweed and polyphenol stimulates the antioxidant status of the blood, however, it does not affect the haematological profile.

References:
Abdelnour S, Alagawany M, Abd El-Hack M, Sheiha A, Swelum A, Saadeldin I. Growth, carcass traits, blood haematology, serum metabolites, immunity, and oxidative indices of growing rabbits fed diets supplemented with red or black pepper oils. Animals. 2018 Oct;8(10):168. https://doi.org/10.3390/ani8100168
 
Abu Hafsa SH, Khalel MS, El-Gindy YM, Ayman AH. Nutritional potential of marine and freshwater algae as dietary supplements for growing rabbits. Int J Anim Sci. 2021 May 27;20(1):784-93. https://doi.org/10.1080/1828051X.2021.1928557
 
AOAC – Association of Official Analytical Chemists. Official methods of analysis of AOAC International. 17th ed. Gaithersburg, MD, USA: Association of Official Analytical Chemists; 2000.
 
Benzie IF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: The FRAP assay. Anal Biochem. 1996 Jul 15;239(1):70-6. https://doi.org/10.1006/abio.1996.0292
 
Bevan RJ, Durand MF, Hickenbotham PT, Kitas GD, Patel PR, Podmore ID, Griffiths HR, Waller HL, Lunec J. Validation of a novel ELISA for measurement of MDA-LDL in human plasma. Free Radic Biol Med. 2003 Sep 1;35(5):517-27. https://doi.org/10.1016/S0891-5849(03)00359-9
 
Casamassima D, Chiosi F, Vizzarri F, Palazzo M, Costagliola C. The effect of Laurus nobilis on the blood and lenses antioxidant activity in rabbit under fat-enriched diet. Physiol Res. 2017 May 4;66(2):325-33. https://doi.org/10.33549/physiolres.933409
 
Corino C, Modina SC, Di Giancamillo A, Chiapparini S, Rossi R. Seaweeds in pig nutrition. Animals (Basel). 2019 Dec 12;9(12):1126. https://doi.org/10.3390/ani9121126
 
Corino C, Rossi R. Antioxidants in animal nutrition. Antioxidants. 2021;10(12):1877. https://doi.org/10.3390/antiox10121877
 
Cox S, Abu-Ghannam N, Gupta S. An assessment of the antioxidant and antimicrobial activity of six species of edible Irish seaweeds. Int Food Res J. 2010;17(1):205-20.
 
Dalle Zotte A, Celia C, Szendro Z. Herbs and spices inclusion as feedstuff or additive in growing rabbit diets and as additive in rabbit meat: A review. Livestock Sci. 2016;189:82-90. https://doi.org/10.1016/j.livsci.2016.04.024
 
Dominguez H. Functional ingredients from algae for foods and nutraceuticals. Cambridge, UK: Woodhead Publishing Limited; 2013. p. 228-9.
 
El-Nomeary SAA, El-Kady RI, El-Shahat AA, El-Nattat WS. Prolonged effect of some plant seeds meals supplementation on the performance and plasma parameters in male rabbits. Int J Chem Tech Res. 2016;9(12):68-80.
 
Gessner DK, Ringseis R, Eder K. Potential of plant polyphenols to combat oxidative stress and inflammatory processes in farm animals. J Anim Physiol Anim Nutr (Berl). 2017 Aug;101(4):605-28. https://doi.org/10.1111/jpn.12579
 
Hunyadi A. The mechanism(s) of action of antioxidants: From scavenging reactive oxygen/nitrogen species to redox signaling and the generation of bioactive secondary metabolites. Med Res Rev. 2019 Nov;39(6):2505-33. https://doi.org/10.1002/med.21592
 
Ismail E, Abdelnour SA, Sabry SA, El-Hack Mohamed AE, El-Edel Mohamed A, Ayman TE, Schiavitto M, Tufarelli V. Effect of dietary Boswellia serrata resin on growth performance, blood biochemistry, and cecal microbiota of growing rabbits. Front Vet Sci. 2019 Dec 20;6:471. https://doi.org/10.3389/fvets.2019.00471
 
Knizatova N, Massanyi M, Tokarova K, Vizzarri F, Massanyi P, Ondruska L, Lukac N. Effect of dietary supplementation with seaweed and polyphenols mixture on antioxidant status, concentration and motility of rabbit spermatozoa. J Microbiol Biotechnol Food Sci. 2021;10(5):1-4. https://doi.org/10.15414/jmbfs.2179
 
Kovacikova E, Kovacik A, Halenar M, Tokarova K, Chrastinova L, Ondruska L, Jurcik R, Kolesar E, Valuch J, Kolesarova A. Potential toxicity of cyanogenic glycoside amygdalin and bitter apricot seed in rabbits-health status evaluation. J Anim Physiol Anim Nutr (Berl). 2019 Mar;103(2):695-703. https://doi.org/10.1111/jpn.13055
 
Kovacs M, Tuboly T, Mezes M, Balogh K, Gerencser Z, Matics Z, Dal Bosco A, Szendro Z, Tornyos G, Hafner D, Milisits G, Balogh-Zandoki E, Dalle Zotte A. Effect of dietary supplementation of spirulina (Arthrospira platensis) and thyme (Thymus vulgaris) on serum biochemistry, immune response and antioxidant status of rabbits. Ann Anim Sci. 2016;16(1):181-95. https://doi.org/10.1515/aoas-2015-0059
 
Kovitvadhi A, Gai F, Dabbou S, Ferrocino I, Rotolo L, Falzone M, Vignolini C, Gennero MS, Bergagna S, Dezzutto D, Barbero R, Nebbia P, Rosati S, Cocolin L, Zoccarato I, Gasco L. Rabbit dietary supplementation with pale purple coneflower. 2. Effects on the performances, bacterial community, blood parameters and immunity of growing rabbits. Animal. 2016 Jul;10(7):1110-7. https://doi.org/10.1017/S1751731115002980
 
Leineweber C, Muller E, Marschang RE. Blood reference intervals for rabbits (Oryctolagus cuniculus) from routine diagnostic samples. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2018 Dec;46(6):393-8. https://doi.org/10.1055/s-0038-1677403
 
Mahfuz S, Shang Q, Piao X. Phenolic compounds as natural feed additives in poultry and swine diets: A review. J Anim Sci Biotechnol. 2021 Apr 7;12(1):48. https://doi.org/10.1186/s40104-021-00565-3
 
Massanyi M, Kohut L, Argente MJ, Halo M, Kovacik A, Kovacikova E, Ondruska L, Formicki G, Massanyi P. The effect of different sample collection methods on rabbit blood parameters. Saudi J Biol Sci. 2020 Nov;27(11):3157-60. https://doi.org/10.1016/j.sjbs.2020.07.016
 
Mattioli S, Rosignoli P, D’Amato R, Fontanella MC, Regni L, Castellini C, Proietti P, Elia AC, Fabiani R, Beone GM, Businelli D, Dal Bosco A. Effect of feed supplemented with selenium-enriched olive leaves on plasma oxidative status, mineral profile, and leukocyte DNA damage in growing rabbits. Animals (Basel). 2020 Feb 11;10(2):274. https://doi.org/10.3390/ani10020274
 
Melillo A. Rabbit clinical pathology. J Exot Pet Med. 2007 Jul;16(3):135-45. https://doi.org/10.1053/j.jepm.2007.06.002
 
Okab AB, Samara EM, Abdoun KA, Rafay J, Ondruska L, Parkanyi V, Pivko J, Ayoub MA, Alhaidary AA, Aljumaah RS, Massanyi P, Lukac N. Effects of dietary seaweed (Ulva lactuca) supplementation on the reproductive performance of buck and doe rabbits. J App Anim Res. 2013;41(3):347-55. https://doi.org/10.1080/09712119.2013.783479
 
Ozkan C, Kaya A, Akgul Y. Normal values of haematological and some biochemical parameters in serum and urine of New Zealand white rabbits. World Rabbit Sci. 2012;20(4):253-9. https://doi.org/10.4995/wrs.2012.1229
 
Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967 Jul;70(1):158-69.
 
Parasuraman S, Raveendran R, Kesavan R. Blood sample collection in small laboratory animals. J Pharmacol Pharmacother. 2010 Jul;1(2):87-93. Erratum in: J Pharmacol Pharmacother. 2017 Jul-Sep;8(3):153. https://doi.org/10.4103/0976-500X.72350
 
Pavlik A, Jezova D, Zapletal D, Bakos J, Jelinek P. Impact of housing technology on blood plasma corticosterone levels in laying hens. Acta Vet Hung. 2008 Dec;56(4):515-27. https://doi.org/10.1556/avet.56.2008.4.9
 
Pozzo L, Vizzarri F, Ciardi M, Nardoia M, Palazzo M, Casamassima D, Longo V. The effects of fermented wheat powder (Lisosan G) on the blood lipids and oxidative status of healthy rabbits. Food Chem Toxicol. 2015 Oct;84:1-7. https://doi.org/10.1016/j.fct.2015.07.004
 
Rossi R, Vizzarri F, Chiapparini S, Ratti S, Casamassima D, Palazzo M, Corino C. Effects of dietary levels of brown seaweeds and plant polyphenols on growth and meat quality parameters in growing rabbit. Meat Sci. 2020 Mar;161:107987. https://doi.org/10.1016/j.meatsci.2019.107987
 
Russo R, Pucci L, Giorgetti L, Arvay J, Vizzarri F, Longo V, Pozzo L. Polyphenolic characterisation of plant mixture (Lisosan® reduction) and its hypocholesterolaemic effect in high fat diet-fed mice. Nat Prod Res. 2019 Mar;33(5):651-8. https://doi.org/10.1080/14786419.2017.1402328
 
Singer AC, Shaw H, Rhodes V, Hart A. Review of antimicrobial resistance in the environment and its relevance to environmental regulators. Front Microbiol. 2016 Nov 1;7:1728. https://doi.org/10.3389/fmicb.2016.01728
 
Tsiplakou E, Pitino R, Manuelian CL, Simoni M, Mitsiopoulou C, De Marchi M, Righi F. Plant feed additives as natural alternatives to the use of synthetic antioxidant vitamins in livestock animal products yield, quality, and oxidative status: A review. Antioxidants (Basel). 2021 May 14;10(5):780. https://doi.org/10.3390/antiox10050780
 
Tvrda E, Tusimova E, Kovacik A, Paal D, Greifova H, Abdramanov A, Lukac N. Curcumin has protective and antioxidant properties on bull spermatozoa subjected to induced oxidative stress. Anim Reprod Sci. 2016 Sep;172:10-20. https://doi.org/10.1016/j.anireprosci.2016.06.008
 
Valenzuela-Grijalva NV, Pinelli-Saavedra A, Muhlia-Almazan A, Dominguez-Diaz D, Gonzalez-Rios H. Dietary inclusion effects of phytochemicals as growth promoters in animal production. J Anim Sci Technol. 2017 Apr 17;59:8. https://doi.org/10.1186/s40781-017-0133-9
 
Vizzarri F, Palazzo M, Casamassima D, Ondruska L, Massanyi M, Tirpak F, Formicki G, Gren A, Massanyi P. Lippia citriodora (verbascoside) extract supplementation: Effect on rabbit semen quality in vivo and in vitro. Czech J Anim Sci. 2019 Jan;64(1):1-10. https://doi.org/10.17221/35/2018-CJAS
 
Vizzarri F, Chiapparini S, Corino C, Casamassima D, Palazzo M, Parkanyi V, Ondruska L, Rossi R. Dietary supplementation with natural extracts mixture: Effects on reproductive performances, blood biochemical and antioxidant parameters in rabbit does. Ann Anim Sci. 2020;20(2):565-78. https://doi.org/10.2478/aoas-2019-0084
 
Vizzarri F, Massanyi M, Knizatova N, Corino C, Rossi R, Ondruska L, Tirpak F, Halo M, Massanyi P. Effects of dietary plant polyphenols and seaweed extract mixture on male-rabbit semen: Quality traits and antioxidant markers. Saudi J Biol Sci. 2021 Jan;28(1):1017-25. https://doi.org/10.1016/j.sjbs.2020.11.043
 
Zbynovska K, Halenar M, Chrastinova L, Ondruska L, Jur-cik R, Cupka P, Kovacikova E, Kovacik A, Kolesar E, Valuch J, Kolesarov A. Oral and instamuscular application of cyanogenic glycoside amygdalin did not induce changes in haematological profile of male rabbits. Slovak J Food Sci. 2016;11(1):315-21.
 
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