Analgesic effect of intra-articular ropivacaine injection after arthroscopic surgery on the shoulder joint in dogs J.H., Seok S.H., Park T.Y., Kim H.J., Lee S.W., Lee H.C., Yeon S.C. (2018): Analgesic effect of intra-articular ropivacaine injection after arthroscopic surgery on the shoulder joint in dogs. Veterinarni Medicina, 63: 513-521.
download PDF

Shoulder joint disorders are a major cause of forelimb lameness in dogs, and osteochondrosis, degenerative joint disease, and bicipital tenosynovitis are common joint disorders that have been reported in dogs. Many studies have investigated pain management after arthroscopy in human medicine, but reports from veterinary medicine are rare. Ropivacaine is a new amide local anaesthetic drug and a single isomer drug that is used more widely than bupivacaine in human medicine because it has fewer side effects. The present study was conducted to evaluate the analgesic effect of intra-articular injection of ropivacaine after arthroscopic surgery in dog shoulder joints. To accomplish this, ten dogs were randomly divided into two groups of five who underwent the same anaesthesia protocol and shoulder arthroscopic examination. After shoulder arthroscopy, ropivacaine or 0.9% NaCl was injected into the shoulder joint cavity and the dogs were evaluated at one hour, two hours, four hours, six hours, 12 hours and 24 hours after surgery. The evaluated parameters were heart rate, respiratory rate, lameness score, visual analogue scale and the short form of the Glasgow composite measure pain scale. Ropivacaine showed a higher analgesic effect than 0.9% NaCl, indicating that it may be useful for pain management following arthroscopic surgery in dogs.

Aarnes T. K., Hubbell J. A. E., Hildreth B. E. (2014): Use of sedation and ropivacaine-morphine epidural for femoral head and neck ostectomy in a dog. Journal of Small Animal Practice, 55, 334-336
Abimussi Caio JX, Menegheti Thais M, Wagatsuma Juliana T, Floriano Beatriz P, Arruda André MM, dos Santos Paulo SP, Oliva Valéria NLS (2014): Tumescent local anesthesia with ropivacaine in different concentrations in bitches undergoing mastectomy: plasma concentration and post-operative analgesia. Veterinary Anaesthesia and Analgesia, 41, 516-525
Albright George A. (1979): Cardiac Arrest Following Regional Anesthesia with Etidocaine or Bupivacaine. Anesthesiology, 51, 285-287
Albuquerque Verônica Batista de, Araújo Marcelo Augusto de, Ferreira Gabriel Thadeu Nogueira Martins, Fonseca Mariana Werneck, Arruda André Moreira Martins, ShiChen Lu, Oliva Valéria Nobre Leal de Souza (2015): Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia. Acta Cirurgica Brasileira, 30, 222-238
Allen Gregory C., St. Amand Marc A., Lui Anne C.P., Johnson Donald H., Lindsay M Patrice (1993): Postarthroscopy Analgesia with Intraarticular Bupivacaine/Morphine. Anesthesiology, 79, 475-480
Beale BS, Hulse DA, Schulz KS, Whitney WO (2003): 3. Arthroscopically assisted surgery of the shoulder joint. In: Beale BS, Hulse DA, Schulz KS, Whitney WO (eds): Small Animal Arthroscopy. 1st edn. Saunders. 23–49.
Bjordal Jan Magnus, Ljunggren Anne Elisabeth, Klovning Atle, Slørdal Lars (2004): Non-steroidal anti-inflammatory drugs, including cyclo-oxygenase-2 inhibitors, in osteoarthritic knee pain: meta-analysis of randomised placebo controlled trials. BMJ, 329, 1317-
Boden Barry P., Fassler Steven, Cooper Suzane, Marchetto Paul A., Moyer Raymond A. (1994): Analgesic effect of intraarticular morphine, bupivacaine, and morphine/bupivacaine after arthroscopic knee surgery. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 10, 104-107
Brouwer R. W., Bierma-Zeinstra S. M. A., van Raaij T. M., Verhaar J. A. N. (2006): Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a Puddu plate. The Journal of Bone and Joint Surgery. British volume, 88-B, 1454-1459
Convery P. N., Milligan K. R., Quinn P., Scott K., Clarke R. C. N. (1998): Low-dose intra-articular ketorolac for pain relief following arthroscopy of the knee joint. Anaesthesia, 53, 1125-1129
Cook James L., Tomlinson James L., Kreeger John M., Cook Cristi Reeves (2016): Induction of Meniscal Regeneration in Dogs Using a Novel Biomaterial. The American Journal of Sports Medicine, 27, 658-665
Crane SW (1987): Perioperative analgesia: A surgeon’s perspective. Journal of the American Veterinary Medical Association 191, 1254–1257.
De Andr??s J., Bellver J., Barrera L., Febre E., Bolinches R. (1993): A Comparative Study of Analgesia After Knee Surgery with Intraarticular Bupivacaine, Intraarticular Morphine, and Lumbar Plexus Block. Anesthesia & Analgesia, 77, 727???730-
Elden Helen, Ladfors Lars, Olsen Monika Fagevik, Ostgaard Hans-Christian, Hagberg Henrik (2005): Effects of acupuncture and stabilising exercises as adjunct to standard treatment in pregnant women with pelvic girdle pain: randomised single blind controlled trial. BMJ, 330, 761-
Ender Stephan Albrecht, Wetterau Elmar, Ender Michaela, Kühn Jens-Peter, Merk Harry Rudolf, Kayser Ralph, Eldabe Sam (2013): Percutaneous Stabilization System Osseofix® for Treatment of Osteoporotic Vertebral Compression Fractures - Clinical and Radiological Results after 12 Months. PLoS ONE, 8, e65119-
Feldman Hal S., Arthur G. Richard, Covino Benjamin G. (1989): Comparative Systemic Toxicity of Convulsant and Supraconvulsant Doses of Intravenous Ropivacaine, Bupivacaine, and Lidocaine in the Conscious Dog. Anesthesia & Analgesia, 69, 794???801-
Hanesch U, Heppelmann B, MeBlinger K, Schmidt R (1992): Nociception in normal and arthritic joints: structural and functional aspects. Hyperalgesia and Allodynia, 81–106.
Hansen B. D. (2003): Assessment of Pain in Dogs: Veterinary Clinical Studies. ILAR Journal, 44, 197-205
Hennig Geoffrey S., Hosgood Giselle, Bubenik-Angapen Loretta J., Lauer Susanne K., Morgan Timothy W. (2010): Evaluation of chondrocyte death in canine osteochondral explants exposed to a 0.5% solution of bupivacaine. American Journal of Veterinary Research, 71, 875-883
Hoelzler Michael G., Harvey Ralph C., Lidbetter David A., Millis Darryl L. (2005): Comparison of Perioperative Analgesic Protocols for Dogs Undergoing Tibial Plateau Leveling Osteotomy. Veterinary Surgery, 34, 337-344
Holton L. L., Scott E. M., Nolan A. M., Reid J., Welsh E. (1998): Relationship between physiological factors and clinical pain in dogs scored using a numerical rating scale. Journal of Small Animal Practice, 39, 469-474
Holton L., Pawson P., Nolan A., Reid J., Scott E. M. (2001): Development of a behaviour-based scale to measure acute pain in dogs. Veterinary Record, 148, 525-531
Huskisson E.C (1974): MEASUREMENT OF PAIN. The Lancet, 304, 1127-1131
Khoury George F., Chen Andrew C. N., Garland Douglas E., Stein Christoph (1992): Intraarticular Morphine, Bupivacaine, and Morphine/Bupivacaine for Pain Control after Knee Videoarthroscopy. Anesthesiology, 77, 263-266
Laflamme D (1997): Development and validation of a body condition score system for dogs. Canine Practice 22, 10–15.
Lewis Kerrie A., Bednarski Richard M., Aarnes Turi K., Dyce Jonathan, Hubbell John A. E. (2014): Postoperative comparison of four perioperative analgesia protocols in dogs undergoing stifle joint surgery. Journal of the American Veterinary Medical Association, 244, 1041-1046
Li Yue-Ming, Wingrove Douglas E., Too Phon H., Marnerakis Margarita, Stimson Evelyn R., Strichartz Gary R., Maggio John E. (1995): Local Anesthetics Inhibit Substance P Binding and Evoked Increases in Intracellular Calcium sup 2+. Anesthesiology, 82, 166-173
Mathews KA, Paley DM, Foster RA, Valliant AE, Young SS (1996): A comparison of ketorolac with flunixin, butorphanol, and oxymorphone in controlling postoperative pain in dogs. Canadian Veterinary Journal 37, 557–567.
MCCRAE A.F., JOZWIAK H., MCCLURE J.H. (1995): Comparison of ropivacaine and bupivacaine in extradural analgesia for the relief of pain in labour. British Journal of Anaesthesia, 74, 261-265
McILWRAITH C. W. (1984): Experiences in diagnostic and surgical arthroscopy in the horse. Equine Veterinary Journal, 16, 11-19
Merson N (2001): A comparison of motor block between ropivacaine and bupivacaine for continuous labor epidural analgesia. American Association of Nurse Anesthetists Journal 69, 54–58.
Møiniche Steen, Mikkelsen Søren, Wetterslev Jørn, Dahl Jørgen Berg (1999): A Systematic Review of Intra-articular Local Anesthesia for Postoperative Pain Relief After Arthroscopic Knee Surgery. Regional Anesthesia and Pain Medicine, 24, 430-437
Morton C (1997): New drugs: Ropivacaine. British Journal of Hospital Medicine 58, 97–100.
Morton D., Griffiths P. (1985): Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment. Veterinary Record, 116, 431-436
Munroe G.A., Cauvin E.R. (1994): The use of arthroscopy in the treatment of septic arthritis in two highland calves. British Veterinary Journal, 150, 439-449
Olivieri M., Ciliberto E., Hulse D. A., Vezzoni A., Ingravalle F., Peirone B. (2017): Arthroscopic treatment of osteochondritis dissecans of the shoulder in 126 dogs. Veterinary and Comparative Orthopaedics and Traumatology, 20, 65-691
Pitkanen M, Feldman HS, Arthur GR, Covino BG (1992): Chronotropic and inotropic effects of ropivacaine, bupivacaine, and lidocaine in the spontaneously beating and electrically paced isolated, perfused rabbit heart. Regional Anesthesia 17, 183–192.
Raušer P., Dvořák M., Nečas A., Lexmaulová L., Novotná R. (2005): Effect of Intraarticular Bupivacaine Administration on Postoperative Pain Relief after Arthrotomic or Arthroscopic Management of Cranial Cruciate Ligament Rupture in Dogs. Acta Veterinaria Brno, 74, 613-619
Reid J., Nolan A. M. (1991): A comparison of the postoperative analgesic and sedative effects of flimixin and pap aver etum in the dog. Journal of Small Animal Practice, 32, 603-608
Reid J, Nolan AM, Hughes JML, Lascelles D, Pawson P, Scott EM (2007): Development of the short-form Glasgow Composite Measure Pain Scale (CMPS-SF) and derivation of an analgesic intervention score. Animal Welfare 16, 97–104.
REIZ S., HÄGGMARK S., JOHANSSON G., NATH S. (1989): Cardiotoxicity of ropivacaine - a new amide local anaesthetic agent. Acta Anaesthesiologica Scandinavica, 33, 93-98
Richmond Stewart J., Gunadasa Shalmini, Bland Martin, MacPherson Hugh, Eldabe Sam (2013): Copper Bracelets and Magnetic Wrist Straps for Rheumatoid Arthritis – Analgesic and Anti-Inflammatory Effects: A Randomised Double-Blind Placebo Controlled Crossover Trial. PLoS ONE, 8, e71529-
SAMMARCO JILL L., CONZEMIUS MICHAEL G., PERKOWSKI SANDRA Z., WEINSTEIN M. JOY, GREGOR THOMAS P., SMITH GAIL K. (1996): Postoperative Analgesia for Stifle Surgery: A Comparison of Intra-articular Bupivacaine, Morphine, or Saline. Veterinary Surgery, 25, 59-69
Scott J, Huskisson E C (1979): Accuracy of subjective measurements made with or without previous scores: an important source of error in serial measurement of subjective states.. Annals of the Rheumatic Diseases, 38, 558-559
Scott D. Bruce, Lee Alistair, Fagan Denise, Bowler Geoffrey M. R., Bloomfield Peter, Lundh Rolf (1989): Acute Toxicity of Ropivacaine Compared with That of Bupivacaine. Anesthesia & Analgesia, 69, 563???569-
Sengupta Nishan, Nichol Michael B., Wu Joanne, Globe Denise (2004): Mapping the SF-12 to the HUI3 and VAS in a Managed Care Population. Medical Care, 42, 927-937
Soto Natalia, Fauber Amy E., Ko Jeff C. H., Moore George E., Lambrechts Nicolaas E. (2014): Analgesic effect of intra-articularly administered morphine, dexmedetomidine, or a morphine-dexmedetomidine combination immediately following stifle joint surgery in dogs. Journal of the American Veterinary Medical Association, 244, 1291-1297
Stein Christoph, Comisel Karin, Haimerl Elisabeth, Yassouridis Alexander, Lehrberger Klaus, Herz Albert, Peter Klaus (1991): Analgesic Effect of Intraarticular Morphine after Arthroscopic Knee Surgery. New England Journal of Medicine, 325, 1123-1126
THORNTON P.D, WATERMAN-PEARSON A.E (1999): Quantification of the pain and distress responses to castration in young lambs. Research in Veterinary Science, 66, 107-118
van Bree Henri J.J., Van Ryssen Bernadette (1998): Diagnostic and Surgical Arthroscopy in Osteochondrosis Lesions. Veterinary Clinics of North America: Small Animal Practice, 28, 161-189
Vintar Neli, Rawal Narinder, Veselko Matjaž (2005): Intraarticular Patient-Controlled Regional Anesthesia After Arthroscopically Assisted Anterior Cruciate Ligament Reconstruction: Ropivacaine/Morphine/Ketorolac Versus Ropivacaine/Morphine. Anesthesia & Analgesia, 101, 573-578
WRIGHT I. M., PHILLIPS T. J., WALMSLEY J. P. (1999): Endoscopy of the navicular bursa: A new technique for the treatment of contaminated and septic bursae. Equine Veterinary Journal, 31, 5-11
Yarnell RW, Ewing DA, Tierney E, Smith MH (1990): Sacralization of epidural block with repeated doses of 0.25% bupivacaine during labor. Regional Anesthesia 15, 275–279.
download PDF

© 2022 Czech Academy of Agricultural Sciences | Prohlášení o přístupnosti