Benign ovarian teratoma in the dog with predominantly nervous tissue: A case report
Ovarian teratomas are rare neoplasms in female dogs, and they are characterised by the proliferation of tissues of embryonic origin. Most teratomas are benign, but a histological diagnosis is important for clinicians. The objective of this article is to describe a benign ovarian teratoma in a dog, which was found on the street and was appearing like pregnant. A veterinary inspection by palpation documented an enlarged abdomen with a mass of tough matter located on the right side in the abdominal-pelvic part. An ultrasound examination presumed neoplastic mass in region of ovary. A bilateral ovariohysterectomy was performed and the subsequent histological evaluation revealed a benign ovarian teratoma with a histochemically and immunohistochemically verified nervous tissue. After one year, no distant metastases were found and the dog was recognised as being clinically healthy without problems. On the basis of the ultrasonography diagnostics and histopathological analyses, we have demonstrated the occurrence of a benign ovarian teratoma in a dog.
Akbulut M, Kelten EC, Ege CB. Mature cystic teratoma with predominantly neurogenic elements – Case report. Aegean Pathol J. 2006 Aug;22(3):18-20.
Blaszak B, Walkowski M, Ibbs M, Jaskowski JM. Teratoma adultum in a bitch: A case report. Vet Med-Czech. 2009 Aug;54(8):379-81.
https://doi.org/10.17221/79/2009-VETMED
Chai Y, Woo CG, Kim JY, Kim CJ, Khang SK, Kim J, Park IA, Kim EN, Kim KR. Diagnostic significance of cellular neuroglial tissue in ovarian immature teratoma. J Pathol Transl Med. 2017 Jan;51(1):49-55.
https://doi.org/10.4132/jptm.2016.09.19
Coggeshall JD, Franks JN, Wilson DU, Wiley JP. Primary ovarian teratoma and GCT with intra-abdominal metastasis in a dog. J Am Anim Hosp Assoc. 2012 Nov-Dec;48(6):424-8.
https://doi.org/10.5326/JAAHA-MS-5809
Da Costa DA, Da Silva MRM, De Souza NF, Pereira WLA, Cardoso AMC. Giant canine ovarian teratoma: Case report. J Cytol Histol. 2017 Aug;8(3):1-3.
https://doi.org/10.4172/2157-7099.1000463
De Bosschere H, Durnez V, Ducatelle R. Malignant ovarian teratoma in a Golden Retriever. Vlaams Diergeneesk Tijdcchr. 1999 Feb;68(2):96-100.
Gulcubuk A, Altun ED, Bozkurt ER, Sontas BS, Haktanir D. Ovarian teratoma in a dog. Turkish J Vet Anim Sci. 2012 May;36(5):573-6.
Iemura Y, Yamada Y, Hirata M, Kataoka TR, Minamiguchi S, Haga H. Histopathological characterization of the neuroglial tissue in ovarian teratoma associated with anti-N-methyl-d-aspartate (NMDA) receptor encephalitis. Pathol Int. 2018 Dec;68(12):677-84.
https://doi.org/10.1111/pin.12732
Linder D, McCaw BK, Hecht F. Parthenogenic origin of benign ovarian teratomas. N Engl J Med. 1975 Jan 9;292(2):63-6.
https://doi.org/10.1056/NEJM197501092920202
Lopez D, Singh A, Wright TF, Gartley C, Walker M. Single incision laparoscopic-assisted ovariohysterectomy for an ovarian tumour in a dog. Can Vet J. 2017 Sep;58(9):975-9.
Makovicky P, Svecova I. Veterinary pathology: The past, present and the future. Phenogenomic Newsletter. 2016 April;2(2):22-3.
Nagashima Y, Hoshi K, Tanaka R, Shibazaki A, Fujiwara K, Konno K, Machida N, Yamane Y. Ovarian and retroperitoneal teratomas in a dog. J Vet Med Sci. 2000 Jul;62(7):793-5.
https://doi.org/10.1292/jvms.62.793
Oviedo-Penata CA, Hincapie L, Benavides CR, Maldonado JG. Concomitant presence of ovarian tumors (teratoma and granulosa cell tumor), and pyometra in an English Bulldog female dog: A case report. Front Vet Sci. 2020 Jan;14(6):500.
https://doi.org/10.3389/fvets.2019.00500
Patnaik AK, Greenlee PG. Canine ovarian neoplasms: A clinic-pathologic study of 71 cases, including histology of 12 granulosa cell tumors. Vet Pathol. 1987 Nov;24(6):509-14.
https://doi.org/10.1177/030098588702400607
Pegas GRA, Monteiro LN, Cassali GD. Extragonadal malignant teratoma in a dog – Case report. Arq Bras Med Vet Zootec. 2020 Jan-Feb;72(1):115-8.
https://doi.org/10.1590/1678-4162-10434
Pires MDA, Catarino JC, Vilhena H, Faim S, Neves T, Freire A, Seixas F, Orge L, Payan-Carreira R. Co-existing monophasic teratoma and uterine adenocarcinoma in a female dog. Reprod Domest Anim. 2019 Jul;54(7):1044-9.
https://doi.org/10.1111/rda.13430
Rota A, Tursi M, Zabarino S, Appino S. Monophasic teratoma of the ovarian remnant in a bitch. Reprod Domest Anim. 2013 Apr;48(2):26-8.
https://doi.org/10.1111/rda.12090
Sarrau S. Iatrogenic ureteral lesion following a bulky ovarian teratoma excision in a 3-year bitch. Rev Veterinaire Clin. 2018 Apr;53(4):115-20.
Stussi A, Bohler A, Zednik T, Shiblz S, Zednik P. Teratoma – A rare ovarian tumour in a bitch. Wien Tierärztl Monatsschr. 2008 Mar;95(3):85-90.
Xiang H, Han J, Ridley WE, Ridley LJ. Canine tooth: Mature cystic teratoma. J Med Imaging Radiat Oncol. 2018 Oct;62(S1):61.
https://doi.org/10.1111/1754-9485.09_12784
Yamaguchi Y, Sato T, Shibuya H, Tsumagari S, Suzuki T. Ovarian teratoma with a formed lens and non-supportive inflammation in an old dog. J Vet Med Sci. 2004 Jul;66(7):861-4.
https://doi.org/10.1292/jvms.66.861
Yoshimura, Yamamoto M, Moriya M, Endo T, Sugiura N, Kato T, Matsuda Y, Ishiwata T, Kajigaya H, Kamiiya S. Teratoma of the ovary in a free-ranging Japanese Raccoon dog (Nyctereutes Procyonoides Viverrinus). J Zoo Wildl Med. 2017 Mar;48(1):265-8.
https://doi.org/10.1638/2016-0026.1
