Carotid body tumour in a dog: computed tomography and histopathology findings and evaluation of surgical management
A 2.5-kg, eight-year-old, neutered male Yorkshire Terrier was presented for evaluation of a cervical mass that had first been noticed a year earlier. A firm spherical mass located caudal to the left mandible was found on physical examination. Ultrasonography revealed a well-defined, round-shaped mass located medial to the left mandibular salivary gland that was approximately 2.6 cm in height, 2.3 cm in width and 3 cm in length. Volume-rendered images obtained by computed tomography (CT) showed that the left external and internal carotid arteries and internal jugular vein were encased in the mass. A definitive diagnosis of carotid body tumour was made based on histopathology. The tumour and the carotid arteries and internal jugular vein encased in the tumour were resected using CT-based surgical planning. The regional neural structures were preserved by careful blunt dissection. The dog had a mild hacking cough after swallowing and hoarseness that disappeared spontaneously five days and two months, respectively, after surgery. There was no evidence of recurrence or distant metastasis at 18 months postoperatively. This case report describes successful surgical management of a carotid body tumour with ligation and transection of the carotid arteries in a dog. To the authors’ knowledge, this is the first report of successful surgical treatment of an advanced carotid body tumour based on CT findings.
Budras KD, McCarthy PH, Fricke W, Richter R (2007): Neck and chest region. In: Budras KD (ed.): Anatomy of the Dog. 5th edn. Schlutersche Verlagsgesellschaft, Hannover. 12–15.
Capen CC (2002): Tumors of the endocrine glands. In: Meuten DJ (ed.): Tumors of Domestic Animals. 4th edn. Iowa State Press, Ames. 607–696.
Clendenin MA, Conrad MC (1979a): Collateral vessel development, following unilateral chronic carotid occlusion in the dog. American Journal of Veterinary Research 40, 84–88.
Clendenin MA, Conrad MC (1979b): Collateral vessel development after chronic bilateral common carotid artery occlusion in the dog. American Journal of Veterinary Research 40, 1244–1248.
Dean MJ, Strafuss AC (1975): Carotid body tumors in the dog: A review and report of four cases. Journal of the American Veterinary Medical Association 166, 1003–1006.
Evans HE, de Lahunta A (2013): Cranial nerves. In: Evans HE, de Lahunta A (eds): Miller’s Anatomy of the Dog. 4th edn. WB Saunders, Philadelphia. 708–730.
Jubb K. V., Kennedy Peter C. (1957): Tumors of the nonchromaffin paraganglia in dogs. Cancer, 10, 89-99 https://doi.org/10.1002/1097-0142(195701/02)10:1<89::AID-CNCR2820100112>3.0.CO;2-K
Luna-Ortiz Kuauhyama, Rascon-Ortiz Mario, Villavicencio-Valencia Verónica, Granados-Garcia Martín, Herrera-Gomez Angel (2005): Carotid body tumors: review of a 20-year experience. Oral Oncology, 41, 56-61 https://doi.org/10.1016/j.oraloncology.2004.06.006
Mai W, Seiler GS, Lindl-Bylicki BJ, Zwingenberger AL (2015): CT and MRI features of carotid body paragangliomas in 16 dogs. Veterinary Radiology & Ultrasound 56, 374–383.
Makeieff M., Raingeard I., Alric P., Bonafe A., Guerrier B., Marty-Ane Ch. (2008): Surgical Management of Carotid Body Tumors. Annals of Surgical Oncology, 15, 2180-2186 https://doi.org/10.1245/s10434-008-9977-z
Obradovich Joyce E., Withrow Stephen J., Powers Barbara E., Walshaw Richard (1992): Carotid Body Tumors in the Dog Eleven Cases (1978-1988). Journal of Veterinary Internal Medicine, 6, 96-101 https://doi.org/10.1111/j.1939-1676.1992.tb03158.x
Patetsios Peter, Gable Dennis R., Garrett Wilson V., Lamont Jeffrey P., Kuhn Joseph A., Shutze William P., Kourlis Harry, Grimsley Bradley, Pearl Gregory J., Smith Bertram L., Talkington C.M., Thompson Jesse E. (2002): Management of Carotid Body Paragangliomas and Review of a 30-year Experience. Annals of Vascular Surgery, 16, 331-338 https://doi.org/10.1007/s10016-001-0106-8
Phan A, Yates GD, Nimmo J, Holloway SA (2013): Syncope associated with swallowing in two British Bulldogs with unilateral carotid body tumours. Australian Veterinary Journal, 91, 47-51 https://doi.org/10.1111/avj.12016
Sajid M.S., Hamilton G., Baker D.M. (2007): A Multicenter Review of Carotid Body Tumour Management. European Journal of Vascular and Endovascular Surgery, 34, 127-130 https://doi.org/10.1016/j.ejvs.2007.01.015
Sander CH, Whitenack DL (1970): Canine malignant carotid body tumor. Journal of the American Veterinary Medical Association 156, 606–610.
Shamblin William R., ReMine William H., Sheps Sheldon G., Harrison Edgar G. (1971): Carotid body tumor (chemodectoma). The American Journal of Surgery, 122, 732-739 https://doi.org/10.1016/0002-9610(71)90436-3
Taeymans O, Penninck DG, Peters RM (2013): Comparison between clinical ultrasound, CT, MRI, and pathology findings in dogs presented for suspected thyroid carcinoma. Veterinary Radiology & Ultrasound 54, 61–70.
ZAKARIAN B., NAGHSHINEH R., SANJAR M. (1972): Aortic body and carotid body tumours in dogs in Iran (A record of six cases). Journal of Small Animal Practice, 13, 249-256 https://doi.org/10.1111/j.1748-5827.1972.tb06342.x