Malignant peripheral nerve sheath tumour in a dog presenting as a pseudo aneurysm of the left jugular vein: a case report

https://doi.org/10.17221/1976-VETMEDCitation:Kostov M., Mijovic Z., Visnjic M., Mihailovic D., Stojanovic M., Zdravkovic M. (2008): Malignant peripheral nerve sheath tumour in a dog presenting as a pseudo aneurysm of the left jugular vein: a case report. Veterinarni Medicina, 53: 685-689.
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The authors report an autopsy case of a malignant peripheral nerve sheath tumour in a 9-year-old female Akito-ino dog, presenting as a pseudo aneurysm of the left jugular vein. Signs and symptoms included swelling of the neck and legs, dyspnea, malaise and weight loss. Post-mortem examination revealed a tumour mass (8 × 6, 5 × 6 cm), localized to the left paravertebrally, and on the level of C7 to T2 vertebral bodies; additional masses were observed in both lungs, heart and left kidney. On the basis of necropsy, histological findings and immunophenotype, the tumour was classsified as a malignant peripheral nerve sheath tumour. Immunohistochemistry especially positivity for S-100 protein can be helpful in distinguishing this type of neoplasm from other malignancies with similar morphologies.
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