Post-calving administration of uterine stimulants does not improve reproductive performance in dairy cows

https://doi.org/10.17221/8492-VETMEDCitation:Holickova K., Dolezel R., Cech S. (2015): Post-calving administration of uterine stimulants does not improve reproductive performance in dairy cows. Veterinarni Medicina, 60: 539-543.
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The aim of this study was to evaluate the effects of administration of oxytocin, in combination with dinoprost or ergometrin, after parturition on the occurrence of clinical endometritis and subsequent reproductive performance in dairy cows. The cows, without retained foetal membranes, were assigned to one of three groups. No treatment was performed in the control group (Group C, n = 229). However, intramuscular administrations of oxytocin (30 IU) on Days 1 and 2 post partum, in combination with dinoprost (25 mg, Group D, n = 123) or ergometrin (15 mg, Group E, n = 130) administered on Day 7 post partum, were performed in experimental groups. Vaginal discharge score (VDS, 1–5), uterine content score (UCS, 1–3) on Day14 to 21 post partum, number of treatment interventions (TI), proportion of non-treated cows (NT) because of endometritis, calving to first insemination interval (CI), first insemination conception rate (CR), and proportion of pregnant cows by Day 150 post partum (PC), were compared among groups. There was no significant difference among groups for any parameter. Average values were 2.08, 2.24 and 2.06 (VDS); 1.49, 1.51 and 1.45 (UCS); 0.86, 0.93 and 0.74 (TI); 59.4, 54.2 and 54.7% (NT); 73.9 ± 15.2, 75.4 ± 17 and 74.2 ± 17 days (CI); 41.4, 38.9 and 44.3% (CR); and 75.4, 77.7 and 80.5% (PC) for Groups C, D and E, respectively. There was no significant benefit of preventive administration of oxytocin, in combination with dinoprost or ergometrin, after parturition on reproductive performance in dairy cows.
References:
Bajcsy Árpád Csaba, Szenci Ottó, Weijden Gijsbert C. van der, Doornenbal Arie, Maassen Francesca, Bartyik János, Taverne Marcel A.M. (2006): The effect of a single oxytocin or carbetocin treatment on uterine contractility in early postpartum dairy cows. Theriogenology, 65, 400-414  https://doi.org/10.1016/j.theriogenology.2005.05.040
 
Barrett A. J., Murray R. D., Christley R. M., Dobson H., Smith R. F. (2009): Effects of the administration of oxytocin or carbetocin to dairy cows at parturition on their subsequent fertility. Veterinary Record, 165, 623-626  https://doi.org/10.1136/vr.165.21.623
 
Borsberry S., Dobson H. (1989): Periparturient diseases and their effect on reproductive performance in five dairy herds. Veterinary Record, 124, 217-219  https://doi.org/10.1136/vr.124.9.217
 
Dolezel R, Vecera M, Palenik T, Cech S, Vyskocil M (2008): Systematic clinical examination of early postpartum cows and treatment of puerperal metritis did not have any beneficial effect on subsequent reproductive performance. Veterinarni Medicina 53, 59–69.
 
Dubuc J., Duffield T.F., Leslie K.E., Walton J.S., LeBlanc S.J. (2011): Randomized clinical trial of antibiotic and prostaglandin treatments for uterine health and reproductive performance in dairy cows. Journal of Dairy Science, 94, 1325-1338  https://doi.org/10.3168/jds.2010-3757
 
Fourichon C., Seegers H., Malher X. (2000): Effect of disease on reproduction in the dairy cow: a meta-analysis. Theriogenology, 53, 1729-1759  https://doi.org/10.1016/S0093-691X(00)00311-3
 
Gajewski Z, Thun R, Faundez R, Boryczko Z (1999): Uterine Motility in the Cow During Puerperium. Reproduction in Domestic Animals, 34, 185-191  https://doi.org/10.1111/j.1439-0531.1999.tb01239.x
 
Haimerl P., Heuwieser W., Arlt S. (2013): Therapy of bovine endometritis with prostaglandin F2α: A meta-analysis. Journal of Dairy Science, 96, 2973-2987  https://doi.org/10.3168/jds.2012-6154
 
Hickey G., White M., Wickenden R., Armstrong D. (1984): Effects of oxytocin on placental retention following dystocia. Veterinary Record, 114, 189-190  https://doi.org/10.1136/vr.114.8.189
 
Hirsbrunner G, Küpfer U, Burkhardt H, Steiner A (1998): Effect of different prostaglandins on intrauterine pressure and uterine motility during diestrus in experimental cows. Theriogenology, 50, 445-455  https://doi.org/10.1016/S0093-691X(98)00151-4
 
Kaufmann T.B., Westermann S., Drillich M., Plöntzke J., Heuwieser W. (2010): Systemic antibiotic treatment of clinical endometritis in dairy cows with ceftiofur or two doses of cloprostenol in a 14-d interval. Animal Reproduction Science, 121, 55-62  https://doi.org/10.1016/j.anireprosci.2010.04.190
 
Kaya D, Ay SS, Kucukaslan I, Beceriklisoy HB, Agaoglu AR, Findik M, Ozyurtlu N, Aslan S (2012): The effectiveness of combined preventive treatment with ceftiofur, oxytocin and PGF2α on fertility parameters in cows. Revue de Medecine Veterinaire 163, 302–308.
 
Kudlac E, Zamecnik B (1984): Effects of carbetocin (Depotocin inj. Spofa) on prevention of retained placenta in postpartum cows (in Czech). Biologizace a chemizace zivocisne vyroby – veterinaria 20, 131–140.
 
McClary D.G., Putnam M.R., Wright J.C., Sartin J.L. (1989): Effect of early postpartum treatment with prostaglandin F2α on subsequent fertility in the dairy cow. Theriogenology, 31, 565-570  https://doi.org/10.1016/0093-691X(89)90241-0
 
McDougall S., Macaulay R., Compton C. (2007): Association between endometritis diagnosis using a novel intravaginal device and reproductive performance in dairy cattle. Animal Reproduction Science, 99, 9-23  https://doi.org/10.1016/j.anireprosci.2006.03.017
 
McDougall Scott, de Boer Melvin, Compton Chris, LeBlanc Stephen J. (2013): Clinical trial of treatment programs for purulent vaginal discharge in lactating dairy cattle in New Zealand. Theriogenology, 79, 1139-1145  https://doi.org/10.1016/j.theriogenology.2013.02.002
 
McLaughlin C.L., Stanisiewski E.P., Risco C.A., Santos J.E.P., Dahl G.E., Chebel R.C., LaGrow C., Daugherty C., Bryson L., Weigel D., Hallberg J., Lucas M.J. (2013): Evaluation of ceftiofur crystalline free acid sterile suspension for control of metritis in high-risk lactating dairy cows. Theriogenology, 79, 725-734  https://doi.org/10.1016/j.theriogenology.2012.11.029
 
Mollo A., Veronesi M.C., Cairoli F., Soldano F. (1997): The use of oxytocin for the reduction of cow placental retention, and subsequent endometritis. Animal Reproduction Science, 48, 47-51  https://doi.org/10.1016/S0378-4320(97)00038-9
 
Palomares R.A., Gutiérrez J.C., Portillo G., Boscan J.C., Montero M., López Y., Maxwell H.S., Carson R.L., Soto E. (2010): Oxytocin treatment immediately after calving does not reduce the incidence of retained fetal membranes or improve reproductive performance in crossbred Zebu cows. Theriogenology, 74, 1414-1419  https://doi.org/10.1016/j.theriogenology.2010.06.013
 
Sheldon I. Martin, Lewis Gregory S., LeBlanc Stephen, Gilbert Robert O. (2006): Defining postpartum uterine disease in cattle. Theriogenology, 65, 1516-1530  https://doi.org/10.1016/j.theriogenology.2005.08.021
 
Sheldon I. Martin, Williams Erin J., Miller Aleisha N.A., Nash Deborah M., Herath Shan (2008): Uterine diseases in cattle after parturition. The Veterinary Journal, 176, 115-121  https://doi.org/10.1016/j.tvjl.2007.12.031
 
Tsousis G, Sharifi AR, Hoedemaker M (2010): Increased Risk of Conception Failure in German Holstein Friesian Cows with Chronic Endometritis. Reproduction in Domestic Animals, 45, 1114-1117  https://doi.org/10.1111/j.1439-0531.2009.01481.x
 
Williams EJ (2013): Drivers of Post-partum Uterine Disease in Dairy Cattle. Reproduction in Domestic Animals, 48, 53-58  https://doi.org/10.1111/rda.12205
 
Williams Erin J., Fischer Deborah P., Pfeiffer Dirk U., England Gary C.W., Noakes David E., Dobson Hilary, Sheldon I.Martin (2005): Clinical evaluation of postpartum vaginal mucus reflects uterine bacterial infection and the immune response in cattle. Theriogenology, 63, 102-117  https://doi.org/10.1016/j.theriogenology.2004.03.017
 
Young I.M., Anderson D.B. (1986): Improved reproductive performance from dairy cows treated with dinoprost tromethamine soon after calving. Theriogenology, 26, 199-208  https://doi.org/10.1016/0093-691X(86)90024-5
 
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