Possible vertical transmission of Babesia canis canis from a bitch to her puppies: a case report

https://doi.org/10.17221/8881-VETMEDCitation:Adaszek L., Obara-Galek J., Piech T., Winiarczyk M., Kalinowski M., Winiarczyk S. (2016): Possible vertical transmission of Babesia canis canis from a bitch to her puppies: a case report. Veterinarni Medicina, 61: 263-266.
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The present study reports the possible vertical transmission of Babesia canis canis from an infected bitch to her puppies. The study concerns a bitch that had developed babesiosis in week seven of pregnancy and her litter, three puppies that exhibited symptoms of the disease in Weeks 8–9 post-partum. In all animals, the infection with protozoa was confirmed by the results of a PCR blood test. The identity of the nucleotide sequences of the amplified fragment of the gene (18S RNA) isolated from the blood of the puppies and the bitch was 100%, which indicates that all the dogs were infected with the same strain of protozoa. This result, together with the exclusion of other possible routes of babesiosis transmission in puppies, suggests that they were infected with Babesia canis canis in utero.
Adaszek Lukasz, Winiarczyk Stanislaw (2008): Molecular characterization of Babesia canis canis isolates from naturally infected dogs in Poland. Veterinary Parasitology, 152, 235-241  https://doi.org/10.1016/j.vetpar.2007.12.024
Adaszek L, Winiarczyk S, Skrzypczak M (2009): The clinical course of babesiosis in 76 dogs infected with protozoa parasites Babesia canis canis. Polish Journal of Veterinary Sciences 12, 81–87.
Adaszek Łukasz, Martinez Alfonso Carbonero, Winiarczyk Stanisław (2011): The factors affecting the distribution of babesiosis in dogs in Poland. Veterinary Parasitology, 181, 160-165  https://doi.org/10.1016/j.vetpar.2011.03.059
Allsopp M.T.E.P., Lewis B.D., Penzhorn B.L. (2007): Molecular evidence for transplacental transmission of Theileria equi from carrier mares to their apparently healthy foals. Veterinary Parasitology, 148, 130-136  https://doi.org/10.1016/j.vetpar.2007.05.017
Cardoso Luís, Costa Álvaro, Tuna Joana, Vieira Lisete, Eyal Osnat, Yisaschar-Mekuzas Yael, Baneth Gad (2008): Babesia canis canis and Babesia canis vogeli infections in dogs from northern Portugal. Veterinary Parasitology, 156, 199-204  https://doi.org/10.1016/j.vetpar.2008.05.027
De Vos AJ, Imes GD, Cullen JS (1976): Cerebral babesiosis in a new-born calf. Onderstepoort Journal of Veterinary Research 43, 75–78.
Fukumoto Shinya, Suzuki Hiroshi, Igarashi Ikuo, Xuan Xuenan (2005): Fatal experimental transplacental Babesia gibsoni infections in dogs. International Journal for Parasitology, 35, 1031-1035  https://doi.org/10.1016/j.ijpara.2005.03.018
Kubelová Michaela, Tkadlec Emil, Bednář Marek, Roubalová Eva, Široký Pavel (2011): West-to-east differences of Babesia canis canis prevalence in Dermacentor reticulatus ticks in Slovakia. Veterinary Parasitology, 180, 191-196  https://doi.org/10.1016/j.vetpar.2011.03.033
Matijatko Vesna, Torti Marin, Schetters Theo P. (2012): Canine babesiosis in Europe: how many diseases?. Trends in Parasitology, 28, 99-105  https://doi.org/10.1016/j.pt.2011.11.003
Mierzejewska Ewa, Welc-Falęciak Renata, Bednarska Małgorzata, Rodo Anna, Bajer Anna (2014): The first evidence for vertical transmission of Babesia canis in a litter of Central Asian Shepherd dogs. Annals of Agricultural and Environmental Medicine, 21, 500-503  https://doi.org/10.5604/12321966.1120590
Milczak A, Riha T, Abramowicz B, Madej E (2004): Hemostatic disorders during the course of canine babesiosis. Medycyna Weterynaryjna 60, 1067–1070.
Neitz W. O. (1956): CLASSIFICATION, TRANSMISSION, AND BIOLOGY OF PIROPLASMS OF DOMESTIC ANIMALS. Annals of the New York Academy of Sciences, 64, 56-111  https://doi.org/10.1111/j.1749-6632.1956.tb36607.x
PÉREZ ENRIQUE, JAÉN MARCELINO, HERRERO MARCO V. (1996): Effect of Management and Inherent Factors on Birth Seropositivity and Seroconversion to Babesia bovis in Calves in Costa Rica. Annals of the New York Academy of Sciences, 791, 100-109  https://doi.org/10.1111/j.1749-6632.1996.tb53516.x
Simões Paula, Cardoso Luís, Araújo Manuela, Yisaschar-Mekuzas Yael, Baneth Gad (2011): Babesiosis due to the canine Babesia microti-like small piroplasm in dogs - first report from Portugal and possible vertical transmission. Parasites & Vectors, 4, 50-  https://doi.org/10.1186/1756-3305-4-50
Solano-Gallego L., Trotta M., Carli E., Carcy B., Caldin M., Furlanello T. (2008): Babesia canis canis and Babesia canis vogeli clinicopathological findings and DNA detection by means of PCR-RFLP in blood from Italian dogs suspected of tick-borne disease. Veterinary Parasitology, 157, 211-221  https://doi.org/10.1016/j.vetpar.2008.07.024
Yeruham I., Avidar Y., Aroch I., Hadani A. (2003): Intra-uterine Infection with Babesia bovis in a 2-day-old Calf. Journal of Veterinary Medicine Series B, 50, 60-62  https://doi.org/10.1046/j.1439-0450.2003.00597.x
Zahler Monika, Schein Eberhard, Rinder Heinz, Gothe Rainer (1998): Characteristic genotypes discriminate between Babesia canis isolates of differing vector specificity and pathogenicity to dogs. Parasitology Research, 84, 544-548  https://doi.org/10.1007/s004360050445
Zygner W, Rapacka G, Gojska-Zygner O (2007): Biochemical abnormalities observed in serum of dogs infected with large Babesia in Warsaw (Poland). Polish Journal of Veterinary Sciences 10, 245–253.
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